CAS 3473-63-0

Formamidine acetate

Description:

Formamidine acetate, with the CAS number 3473-63-0, is an organic compound characterized by its amine and acetate functional groups. It typically appears as a white to off-white crystalline solid and is soluble in water, which makes it useful in various chemical applications. The compound is known for its role as a reagent in organic synthesis, particularly in the preparation of other nitrogen-containing compounds. Formamidine acetate can act as a source of formamidine, which is valuable in the synthesis of pharmaceuticals and agrochemicals. Its chemical structure features a formamidine moiety linked to an acetate group, contributing to its reactivity and utility in chemical transformations. Additionally, it is important to handle this compound with care, as it may pose certain health and safety risks, necessitating appropriate safety measures during its use in laboratory or industrial settings. Overall, formamidine acetate is a versatile compound with significant applications in synthetic chemistry.

Formula: C₂H₄O₂·CH₄N₂

InChI: InChI=1S/C2H4O2.CH4N2/c1-2(3)4;2-1-3/h1H3,(H,3,4);1H,(H3,2,3)

InChI key: InChIKey=XPOLVIIHTDKJRY-UHFFFAOYSA-N

SMILES: C(=N)N.C(C)(O)=O

Synonyms:

• Acetic acid methanimidamide
• Formamidine acetate (1:1)
• Formamidine acetate salt
• Formamidine acetic acid salt
• Formamidine, monoacetate
• Formamidinium acetate
• Formimidamide acetate
• Imidoformamide Acetate (1:1)
• Iminoformamide acetate
• Methanimidamide Acetate
• Methanimidamide monoacetate
• Methanimidamide, acetate (1:1)
• Methyl 4-Methyl-1,3-Thiazole-5-Carboxylate
• NSC 96608
• Formamidine acetate
• Formamidineacetate,99%
• FAA
• FORMAMIDINE,ACETIC ACID
• Acetic acid·formamidine
• Methanimidamideacetate

Formamidine Acetate

CAS: 3473-63-0

Formula: CH₄N₂·C₂H₄O₂

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 104.11

Ref: 3B-F0154

Formamidine acetate, 99%

CAS: 3473-63-0

Formamidine acetate is used as an intermediate in the synthesis of active pharmaceutical ingredients. It is also used as a condensing agent for the preparation of pyrimidine and imidazole heterocycles. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portf

Formula: C₃H₈N₂O₂

Purity: 99%

Color and Shape: Crystals or powder or crystalline powder, White to pale cream

Molecular weight: 104.11

Ref: 02-A11158

Formamidine acetate

CAS: 3473-63-0

Formula: C₃H₈N₂O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 104.1078

Ref: IN-DA0034YE

Formamidine acetate

CAS: 3473-63-0

Formamidine acetate

Formula: CH₄N₂·CH₃CO₂H

Purity: 98%

Color and Shape: white crystalline solid

Molecular weight: 104.11g/mol

Ref: 54-OR28877

Formamidine acetate

CAS: 3473-63-0

Formula: C₃H₈N₂O₂

Molecular weight: 104.11

Ref: 7W-GK5191

Formamidine Acetate

CAS: 3473-63-0

Purity: 98.0%

Color and Shape: Solid, Crystalline or Powder

Molecular weight: 104.10900115966797

Ref: 10-F043868

Formamidine acetate

Controlled Product

CAS: 3473-63-0

Formamidine acetate is an anti-tuberculosis drug that belongs to the class of aminoglycosides. It has been shown to have a potent cytotoxic effect on malignant brain cells in vitro. Formamidine acetate inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Formamidine acetate also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.

Formula: C₂H₄O₂•CH₄N₂

Purity: Min. 95%

Color and Shape: Off-White Clear Liquid

Molecular weight: 104.11 g/mol

Ref: 3D-FF38201

Formamidine Acetate

CAS: 3473-63-0

Applications Formamidine Acetate is a versatile reactant used in the tetrazine-based cycloadditions applied to pretargeted live cell imaging with norbornene modified monoclonal antibody.
References Devaraj, N., et al.: Bioconjugate Chem., 19, 2297 (2008);

Formula: CH₄N₂•C₂H₄O₂

Color and Shape: Neat

Molecular weight: 44.066005

Ref: TR-F691500