CAS 347841-67-2
:Thymidine-a,a,a,6-d4 (9CI)
Description:
Thymidine-a,a,a,6-d4 (9CI), with the CAS number 347841-67-2, is a deuterated form of thymidine, a nucleoside that is a building block of DNA. The "a,a,a,6-d4" designation indicates that specific hydrogen atoms in the thymidine molecule have been replaced with deuterium, a stable isotope of hydrogen. This modification can be useful in various biochemical and pharmacological studies, particularly in tracing metabolic pathways and understanding nucleic acid interactions. Thymidine itself consists of a pyrimidine base (thymine) linked to a deoxyribose sugar. The presence of deuterium can alter the physical and chemical properties slightly, such as solubility and stability, but it primarily serves as a labeling tool in research. Thymidine is essential in DNA synthesis and repair, and its isotopically labeled variants are valuable in studies involving DNA replication, cellular metabolism, and the development of antiviral therapies.
Formula:C10H10D4N2O5
Synonyms:- Thymidine-A,A,A,6-D4
- Thymidine-Alpha,Alpha,Alpha,6-D4
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Found 4 products.
Thymidine-α,α,α,6-d4
CAS:Controlled Product<p>Applications Thymidine-alpha,alpha,alpha,6-d4 (CAS# 347841-67-2) is a useful isotopically labeled research compound.<br></p>Formula:C10H10D4N2O5Color and Shape:NeatMolecular weight:246.2532Thymidine-a,a,a,6-D4
CAS:Controlled Product<p>Thymidine-a,a,a,6-D4 is a nucleoside analogue that inhibits the replication of the hepatitis B virus. It is an analogue of thymidine and is activated by phosphorylation to its active form. This drug prevents viral replication by inhibiting early events in the viral life cycle. Thymidine-a,a,a,6-D4 has been shown to inhibit the synthesis of viral DNA and to inhibit the incorporation of thymidine into newly synthesized DNA. Thymidine-a,a,a,6-D4 also inhibits telbivudine resistance mutations in vitro.</p>Formula:C10H10N2O5D4Purity:Min. 95%Molecular weight:246.25 g/mol
