CAS 347884-61-1

Glycine,L-histidylglycyl-L-valyl-L-serylglycyl-L-histidylglycyl-L-glutaminyl-L-histidylglycyl-L-valyl-L-histidyl-

Description:

The chemical substance known as Glycine, L-histidylglycyl-L-valyl-L-serylglycyl-L-histidylglycyl-L-glutaminyl-L-histidylglycyl-L-valyl-L-histidyl- is a peptide composed of multiple amino acids, specifically glycine, histidine, valine, serine, and glutamine. Its structure indicates that it is a polypeptide, which is a chain of amino acids linked by peptide bonds. This compound is characterized by its potential biological activity, as peptides often play crucial roles in various physiological processes, including hormone regulation, immune response, and cellular signaling. The presence of histidine suggests that it may have buffering capacity due to the imidazole side chain, which can accept or donate protons depending on the pH. Additionally, the sequence and composition of amino acids can influence its solubility, stability, and interaction with other biomolecules. The CAS number 347884-61-1 uniquely identifies this compound in chemical databases, facilitating research and application in fields such as biochemistry and pharmacology.

Formula: C₅₂H₇₆N₂₂O₁₆

Synonyms:

• Alloferon 1

Alloferon trifluoroacetate

CAS: 347884-61-1

Alloferon is a drug that is used to treat bowel diseases. It has been shown to be effective in mouse tumor models and in the treatment of bowel disease. Alloferon is a complex of two compounds, alloferon A and alloferon B, which are nitrogen-containing molecules with biological properties. These compounds have been shown to have anti-inflammatory properties, including the inhibition of prostaglandin synthesis. Alloferon A and alloferon B are also able to bind to Toll-like receptor 4 (TLR4) and activate it. TLR4 activation leads to the production of proinflammatory cytokines such as tumor necrosis factor-α (TNF-α). Alloferon A and alloferon B also inhibit platelet aggregation through the suppression of phosphodiesterase activity, which reduces the production of cyclic nucleotides. The activity index for this drug is high because it has multiple mechanisms for inhibiting inflammation.

Formula: C₅₂H₇₆N₂₂O₁₆•(C₂HF₃O₂)x

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 1,265.3 g/mol

Ref: 3D-FA13240

Alloferon - in acetate salt

CAS: 347884-61-1

Alloferon is a drug that affects the body's biological processes and has been shown to have anticancer and antimicrobial properties. Alloferon binds to histidine residues on peptidoglycan, inhibiting bacterial cell wall synthesis and the development of resistance to antibiotics. It also interacts with amide groups in proteins, which are essential for their biological activity. In addition, Alloferon binds to peptides in the form of an amide bond. This interaction makes Alloferon a bioinorganic molecule that can be used as an antimicrobial agent against microbial infections.

Formula: C₅₂H₇₅N₂₂O₁₆

Purity: Min. 95%

Molecular weight: 1,264.29 g/mol

Ref: 3D-FA145508