CAS 348-36-7

1H-Indole-2-carboxylic acid, 5-fluoro-, ethyl ester

Description:

1H-Indole-2-carboxylic acid, 5-fluoro-, ethyl ester, with the CAS number 348-36-7, is an organic compound characterized by its indole structure, which consists of a fused benzene and pyrrole ring. The presence of a carboxylic acid group and an ethyl ester functional group contributes to its chemical reactivity and solubility properties. The 5-fluoro substitution on the indole ring enhances its biological activity and can influence its pharmacological properties. This compound is typically used in organic synthesis and may serve as an intermediate in the production of pharmaceuticals or agrochemicals. Its characteristics include moderate polarity due to the carboxylic acid and ester groups, which can affect its interaction with biological systems. Additionally, the indole moiety is known for its role in various biochemical processes, making this compound of interest in medicinal chemistry. Safety and handling precautions should be observed, as with many organic compounds, due to potential toxicity and environmental impact.

Formula: C₁₁H₁₀FNO₂

InChI: InChI=1S/C11H10FNO2/c1-2-15-11(14)10-6-7-5-8(12)3-4-9(7)13-10/h3-6,13H,2H2,1H3

InChI key: InChIKey=VIKOQTQMWBKMNA-UHFFFAOYSA-N

SMILES: C(OCC)(=O)C1=CC=2C(N1)=CC=C(F)C2

Synonyms:

• 1H-Indole-2-carboxylic acid, 5-fluoro-, ethyl ester
• 5-Fluoro-1H-indole-2-carboxylic acid ethyl ester
• 5-Fluoroindole-2-carboxylic acid ethyl ester
• 6-Fluoro-1,3-Benzothiazol-2-Amine
• Indole-2-carboxylic acid, 5-fluoro-, ethyl ester
• ethyl 5-fluoro-1H-indole-2-carboxylate
• Ethyl 5-fluoroindole-2-carboxylate

Ethyl 5-Fluoroindole-2-carboxylate

CAS: 348-36-7

Formula: C₁₁H₁₀FNO₂

Purity: >98.0%(GC)

Color and Shape: White to Yellow to Orange powder to crystal

Molecular weight: 207.20

Ref: 3B-E1035

Ethyl 5-fluoroindole-2-carboxylate, 98%

CAS: 348-36-7

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₁H₁₀FNO₂

Purity: 98%

Color and Shape: White to pale yellow, Crystals or powder or crystalline powder

Molecular weight: 207.21

Ref: 02-L14010

Ethyl 5-fluoroindole-2-carboxylate

CAS: 348-36-7

Formula: C₁₁H₁₀FNO₂

Purity: 96%

Color and Shape: Solid

Molecular weight: 207.2010

Ref: IN-DA003QCM

Ethyl 5-fluoro-1H-indole-2-carboxylate

CAS: 348-36-7

Ethyl 5-fluoro-1H-indole-2-carboxylate

Formula: C₁₁H₁₀FNO₂

Purity: 98%

Color and Shape: beige solid

Molecular weight: 207.20g/mol

Ref: 54-PC902680

5-Fluoroindole-2-carboxylic acid ethyl ester

CAS: 348-36-7

Formula: C₁₁H₁₀FNO₂

Purity: 96%

Color and Shape: Solid, White to off-white microcrystalline powder

Molecular weight: 207.204

Ref: 10-F010194

Ethyl 5-fluoroindole-2-carboxylate

CAS: 348-36-7

Ethyl 5-fluoroindole-2-carboxylate is a cytotoxic compound that belongs to the class of organic compounds called aryl rings. It has been shown to inhibit tumor growth in vitro and in vivo through the inhibition of protein synthesis. The molecular docking studies have shown that this compound binds to the enzyme SMMC-7721 cell, which is involved in DNA transcription and replication. It also inhibits activity of other enzymes, such as kinases and phosphatases, which are involved in cellular processes such as proliferation and differentiation. Ethyl 5-fluoroindole-2-carboxylate may be used for the treatment of blood cancer or monosugar diseases, such as diabetes mellitus or hyperlipidemia.

Formula: C₁₁H₁₀FNO₂

Purity: Min. 95%

Molecular weight: 207.2 g/mol

Ref: 3D-FE56782