CAS 348-75-4

3-(Trifluoromethyl)butyric acid

Description:

3-(Trifluoromethyl)butyric acid, with the CAS number 348-75-4, is an organic compound characterized by the presence of a trifluoromethyl group (-CF3) attached to a butyric acid backbone. This compound features a four-carbon chain with a carboxylic acid functional group (-COOH) at one end and the trifluoromethyl group at the third carbon position. The trifluoromethyl group significantly influences the compound's chemical properties, enhancing its lipophilicity and altering its reactivity compared to non-fluorinated analogs. 3-(Trifluoromethyl)butyric acid is typically a colorless liquid or solid, depending on temperature, and is soluble in organic solvents. It is used in various applications, including as an intermediate in the synthesis of pharmaceuticals and agrochemicals. The presence of fluorine atoms can also impart unique biological activity, making it of interest in medicinal chemistry. Safety considerations should be taken into account when handling this compound, as fluorinated compounds can exhibit different toxicological profiles compared to their non-fluorinated counterparts.

Formula: C₅H₇F₃O₂

InChI: InChI=1/C5H7F3O2/c1-3(2-4(9)10)5(6,7)8/h3H,2H2,1H3,(H,9,10)

SMILES: CC(CC(=O)O)C(F)(F)F

Synonyms:

• 3-Trifluoromethylbutyric acid

3-(Trifluoromethyl)butyric acid, 97%

CAS: 348-75-4

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₅H₇F₃O₂

Purity: 97%

Color and Shape: Liquid, Clear colorless

Molecular weight: 156.10

Ref: 02-L12160

4,4,4-Trifluoro-3-methylbutanoic acid

CAS: 348-75-4

Formula: C₅H₇F₃O₂

Purity: 95%

Color and Shape: Liquid

Molecular weight: 156.1031

Ref: IN-DA007H62

3-(Trifluoromethyl)butanoic acid

CAS: 348-75-4

3-(Trifluoromethyl)butanoic acid

Formula: C₅H₇F₃O₂

Purity: 96%

Color and Shape: clear liquid

Molecular weight: 156.10g/mol

Ref: 54-PC7650

3-Trifluoromethylbutyric acid

CAS: 348-75-4

3-Trifluoromethylbutyric acid is a synthetic compound that has been studied as a potential drug for the treatment of dyslipidemia. 3-Trifluoromethylbutyric acid binds to the enzyme phosphatase, which is a key regulator of lipid metabolism and controls the production of lipids in cells. This binding prevents the phosphatase from breaking down phosphoinositides, leading to an increase in the levels of phosphoinositides. The resulting increase in the levels of these molecules causes an increase in the number of insulin receptors on cell surfaces and leads to an improvement in insulin sensitivity. 3-Trifluoromethylbutyric acid also has binding sites on human cells that are specific for subtype 7, which is associated with lower risk for cardiovascular disease, obesity, and diabetes.

Formula: C₅H₇F₃O₂

Purity: Min. 95%

Color and Shape: Colorless Powder

Molecular weight: 156.1 g/mol

Ref: 3D-FT96532