CAS 34837-67-7

2-[(Phenylsulfonyl)amino]benzoic acid

Description:

2-[(Phenylsulfonyl)amino]benzoic acid, with the CAS number 34837-67-7, is an organic compound characterized by its sulfonamide functional group and carboxylic acid moiety. This compound features a benzoic acid backbone substituted with a phenylsulfonyl group and an amino group, which contributes to its potential as a pharmaceutical intermediate or active ingredient. The presence of the sulfonyl group enhances its solubility in polar solvents and may influence its biological activity. Typically, compounds of this nature exhibit moderate to high melting points and are often crystalline solids at room temperature. They may also demonstrate acidic properties due to the carboxylic acid group, allowing for proton donation in solution. Additionally, the compound may engage in hydrogen bonding, which can affect its reactivity and interaction with biological targets. Overall, 2-[(Phenylsulfonyl)amino]benzoic acid is of interest in medicinal chemistry for its potential therapeutic applications, particularly in the development of anti-inflammatory or analgesic agents.

Formula: C₁₃H₁₁NO₄S

InChI: InChI=1S/C13H11NO4S/c15-13(16)11-8-4-5-9-12(11)14-19(17,18)10-6-2-1-3-7-10/h1-9,14H,(H,15,16)

InChI key: InChIKey=KIAHUXDVSURYKM-UHFFFAOYSA-N

SMILES: N(S(=O)(=O)C1=CC=CC=C1)C2=C(C(O)=O)C=CC=C2

Synonyms:

• 2-(Benzenesulfonamido)benzoic acid
• 2-(Phenylsulfonylamino)benzoic acid
• 2-Benzenesulfonylamino-benzoic acid
• Anthranilic acid, N-(phenylsulfonyl)-
• Benzoic Acid, 2-[(Phenylsulfonyl)Amino]-
• N-(o-Carboxyphenyl)benzenesulfonamide
• 2-[(Phenylsulfonyl)amino]benzoic acid

2-Benzenesulfonamidobenzoic acid

CAS: 34837-67-7

Formula: C₁₃H₁₁NO₄S

Purity: 98%

Molecular weight: 277.2957

Ref: IN-DA00CLT4

2-(Phenylsulfonamido)benzoic acid

CAS: 34837-67-7

2-(Phenylsulfonamido)benzoic acid

Purity: 98%

Molecular weight: 277.3g/mol

Ref: 54-OR1062561

2-[(Phenylsulfonyl)amino]benzoic acid

CAS: 34837-67-7

2-[(Phenylsulfonyl)amino]benzoic acid is a white crystalline solid that is soluble in water and ethanol. It has a melting point of 176°C and a boiling point of 280°C. 2-[(Phenylsulfonyl)amino]benzoic acid binds to DNA by an intercalative mechanism, forming covalent bonds with the bases on the DNA. This binding prevents the DNA from unwinding during replication and transcription, thus inhibiting the synthesis of RNA and protein. The dimers form between two molecules of 2-[(Phenylsulfonyl)amino]benzoic acid, due to hydrogen bonding between the carboxylic acid groups. The crystal structure has been determined for this compound as centrosymmetric with space group P2 1 /c. A benzene ring is found in the molecule, which can form a pyridine ring when exposed to heat or

Formula: C₁₃H₁₁NO₄S

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 277.3 g/mol

Ref: 3D-FP136709