CAS 3485-62-9

Clidinium bromide

Description:

Clidinium bromide is a synthetic anticholinergic medication primarily used to treat gastrointestinal disorders, particularly those associated with excessive gastric acid secretion and spasms, such as peptic ulcers and irritable bowel syndrome. It functions by inhibiting the action of acetylcholine on muscarinic receptors, leading to reduced gastrointestinal motility and secretion. The compound appears as a white to off-white crystalline powder and is typically administered in oral form. Clidinium bromide has a relatively low solubility in water, which can influence its absorption and bioavailability. Its pharmacological effects may include dry mouth, blurred vision, and constipation, which are common side effects associated with anticholinergic drugs. The chemical structure of clidinium bromide includes a quaternary ammonium group, contributing to its pharmacological activity. As with any medication, it is essential to use clidinium bromide under medical supervision to manage potential interactions and contraindications effectively.

Formula: C₂₂H₂₆BrNO₃

InChI: InChI=1/C22H26NO3.BrH/c1-23-14-12-17(13-15-23)20(16-23)26-21(24)22(25,18-8-4-2-5-9-18)19-10-6-3-7-11-19;/h2-11,17,20,25H,12-16H2,1H3;1H/q+1;

InChI key: InChIKey=GKEGFOKQMZHVOW-UHFFFAOYSA-M

SMILES: C(C(OC1C2CC[N+](C)(C1)CC2)=O)(O)(C3=CC=CC=C3)C4=CC=CC=C4.[Br-]

Synonyms:

• 1-Azoniabicyclo[2.2.2]Octane, 3-[(Hydroxydiphenylacetyl)Oxy]-1-Methyl-, Hydrobromide
• 1-Azoniabicyclo[2.2.2]octane, 3-[(2-hydroxy-2,2-diphenylacetyl)oxy]-1-methyl-, bromide (1:1)
• 1-Azoniabicyclo[2.2.2]octane, 3-[(hydroxydiphenylacetyl)oxy]-1-methyl-, bromide
• 1-Methyl-3-(benziloyloxy)quinuclidinium bromide
• 3-Benziloyloxy-1-Methylquinuclidinium Bromide
• 3-Hydroxy-1-methylquinuclidinium bromide, benzilate
• 3-{[Hydroxy(Diphenyl)Acetyl]Oxy}-1-Methyl-1-Azoniabicyclo[2.2.2]Octane Bromide
• Quarzan
• Quarzan bromide
• Quinuclidinium, 3-hydroxy-1-methyl-, bromide, benzilate
• Ro 2-3773
• Ro-3773
• 3-(2,2-diphenyl-2-hydroxyethanoyloxy)-quinuclidiniumbromide
• 3-[(Hydroxyphenylacetyl)oxy]-1-methyl-1-azoniabicyclo[2,2,2]octane Bromide, Ro-2-3773, Quarzan
• CLIDINIUM BROMIDE
• 1-methyl-3-benzil-oxyloxy-quinuclidiniumbromide
• 3-[(HYDROXYPHENYLACETYL)OXY]-1-METHYL-1-AZONIABICYCLO[2,2,2]OCTANE BROMIDE
• 3-((hydroxydiphenylacetyl)oxy)-1-methyl-1-azoniabicyclo(2.2.2)octanbromi
• Clidinium
• benzilicacid,esterwith3-hydroxy-1-methylquinuclidinium
• (1-Methyl-1-azoniabicyclo[2.2.2]octan-8-yl) 2-hydroxy-2,2-diphenylacetate bromide
• 3-[(Hydroxydiphenylacetyl)oxy]-1-methyl-1-azoniabicyclo[2.2.2]octane
• quinuclidinolmethylbromide,benzilate
• 3-[(Hydroxydiphenylacetyl)oxy]-1-methyl-1-azoniabicyclo[2.2.2]octane bromide
• 3-(benziloyloxy)-1-methylquinuclidiniumbromide

Clidinium Bromide

CAS: 3485-62-9

Color and Shape: Neat

Ref: 61-FOR1798.00

Clidinium Bromide

CAS: 3485-62-9

Compounds containing an unfused pyridine ring in the structure, nesoi

Formula: C₂₂H₂₆BrNO₃

Color and Shape: White Powder

Molecular weight: 431.10961

Ref: 45-1135000

1-Azoniabicyclo[2.2.2]octane, 3-[(hydroxydiphenylacetyl)oxy]-1-methyl-,bromide

CAS: 3485-62-9

Formula: C₂₂H₂₆BrNO₃

Purity: 99%

Color and Shape: Solid

Molecular weight: 432.3507

Ref: IN-DA00I6W5

Clidinium bromide

CAS: 3485-62-9

Clidinium bromide (Ro 2-3773), a synthetic anticholinergic, treats peptic ulcers and alleviates abdominal cramps and IBS symptoms.

Formula: C₂₂H₂₆BrNO₃

Purity: 98.89% - 99.86%

Color and Shape: White Crystalline Solid

Molecular weight: 432.35

Ref: TM-T0786

Clidinium bromide

CAS: 3485-62-9

Clidinium bromide

Purity: ≥98%

Molecular weight: 432.35g/mol

Ref: 54-BUP14949

Clidinium Bromide

Controlled Product

CAS: 3485-62-9

Formula: C₂₂H₂₆NO₃·Br

Color and Shape: Neat

Molecular weight: 432.35

Ref: 86-MM1798.00

Clidinium Bromide

CAS: 3485-62-9

Formula: C₂₂H₂₆NO₃Br

Molecular weight: 432.35

Ref: 4Z-C-254001

Clidinium Bromide

Controlled Product

CAS: 3485-62-9

Applications An anticholinergic. Used as an antispasmodic.
References Zhang, L., et al.: Pharm. Res., 25, 1902 (2008), Sanderson, H., et al.: Toxicol Lett., 187, 84 (2009),

Formula: C₂₂H₂₆NO₃·Br

Color and Shape: White Solid

Molecular weight: 432.35

Ref: TR-C576250

Clidinium-d7 Bromide

Controlled Product

CAS: 3485-62-9

Formula: C₂₂D₇H₁₉NO₃·Br

Color and Shape: Neat

Molecular weight: 439.394

Ref: TR-C576252