CAS 34917-77-6
:1H-Indole-1-sulfonamide,2,3-dihydro-
Description:
1H-Indole-1-sulfonamide, 2,3-dihydro- is a chemical compound characterized by its indole structure, which is a bicyclic compound consisting of a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole ring. The sulfonamide functional group is attached to the indole, contributing to its potential biological activity. This compound typically exhibits properties such as solubility in polar solvents, which is influenced by the presence of the sulfonamide group. It may also demonstrate various pharmacological activities, including antibacterial or anti-inflammatory effects, making it of interest in medicinal chemistry. The presence of the dihydro group indicates that the compound may exist in a reduced form, which can affect its reactivity and interaction with biological targets. Overall, 1H-Indole-1-sulfonamide, 2,3-dihydro- is a compound of interest in both synthetic and medicinal chemistry due to its unique structural features and potential applications.
Formula:C8H10N2O2S
Synonyms:- 1-Indolinesulfonamide
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Found 2 products.
2,3-Dihydro-1H-indole-1-sulfonamide
CAS:<p>2,3-Dihydro-1H-indole-1-sulfonamide is a potent inhibitor of cellular proliferation and has been shown to be effective in inhibiting the growth of mesenchymal cells. It also has potential use in treating heart disease and cancer. 2,3-Dihydro-1H-indole-1-sulfonamide inhibits tumor growth by inducing apoptotic signaling in the cells. The drug binds to bcl2 protein and inhibits its phosphorylation at Ser70, thereby blocking activation of the mitochondrial pathway. This prevents the release of cytochrome c from mitochondria into cytosol, which leads to cell death.br>br><br>2,3-Dihydro-1H-indole-1-sulfonamide is structurally related to indoleamine 2,3 dioxygenase (IDO) inhibitors that are used for immunotherapy of cancer. The drug binds</p>Formula:C8H10N2O2SPurity:Min. 95%Molecular weight:198.24 g/mol
