CAS 34970-69-9

Burimamide

Description:

Burimamide is a chemical compound classified as a histamine H2 receptor antagonist, primarily used in the treatment of peptic ulcers and gastroesophageal reflux disease (GERD). It functions by inhibiting the action of histamine at the H2 receptors in the stomach lining, thereby reducing gastric acid secretion. Burimamide is characterized by its ability to selectively block these receptors, which helps in alleviating symptoms associated with excessive stomach acid. The compound has a relatively low solubility in water, which can affect its bioavailability and absorption in the gastrointestinal tract. Additionally, it may exhibit side effects typical of H2 antagonists, such as headache, dizziness, or gastrointestinal disturbances. Due to its pharmacological properties, burimamide has been studied for its potential therapeutic applications, although it is less commonly used compared to other H2 blockers. As with any medication, it is important to consider its interactions with other drugs and its contraindications in specific patient populations.

Formula: C₉H₁₆N₄S

InChI: InChI=1S/C9H16N4S/c1-10-9(14)12-5-3-2-4-8-6-11-7-13-8/h6-7H,2-5H2,1H3,(H,11,13)(H2,10,12,14)

InChI key: InChIKey=HXRBAVXGYZUSED-UHFFFAOYSA-N

SMILES: C(CCCNC(NC)=S)C1=CN=CN1

Synonyms:

• N-[4-(1H-Imidazol-5-yl)butyl]-N′-methylthiourea
• N-Methyl-N′-[4(5)-imidazolylbutyl]thiourea
• Burimamide
• Thiourea, N-[4-(1H-imidazol-4-yl)butyl]-N′-methyl-
• Thiourea, N-[4-(1H-imidazol-5-yl)butyl]-N′-methyl-

Burimamide

CAS: 34970-69-9

Burimamide is an antagonist of histamine. It appears to block both H2 and H3 histamine receptors.

Formula: C₉H₁₆N₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 212.32

Ref: TM-T23841