CAS 34973-08-5

Gonadorelin acetate

Description:

Gonadorelin acetate is a synthetic decapeptide that serves as a gonadotropin-releasing hormone (GnRH) analog. It is primarily used in medical applications to stimulate the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the anterior pituitary gland, thereby influencing reproductive functions. The substance is characterized by its ability to mimic the natural GnRH, promoting the regulation of the reproductive hormone axis. Gonadorelin acetate is typically administered via injection and is utilized in various clinical settings, including the treatment of certain types of infertility and in diagnostic procedures for assessing pituitary function. Its chemical structure includes an acetate moiety, which enhances its stability and solubility. The compound is generally well-tolerated, though potential side effects may include headache, flushing, or injection site reactions. As with any peptide hormone, its use is subject to careful medical supervision to ensure efficacy and safety in therapeutic applications.

Formula: C₅₅H₇₅N₁₇O₁₃·C₂H₄O₂

InChI: InChI=1/C55H75N17O13.C2H4O2/c1-29(2)19-38(49(80)67-37(9-5-17-60-55(57)58)54(85)72-18-6-10-43(72)53(84)62-25-44(56)75)66-46(77)26-63-47(78)39(20-30-11-13-33(74)14-12-30)68-52(83)42(27-73)71-50(81)40(21-31-23-61-35-8-4-3-7-34(31)35)69-51(82)41(22-32-24-59-28-64-32)70-48(79)36-15-16-45(76)65-36;1-2(3)4/h3-4,7-8,11-14,23-24,28-29,36-43,61,73-74H,5-6,9-10,15-22,25-27H2,1-2H3,(H2,56,75)(H,59,64)(H,62,84)(H,63,78)(H,65,76)(H,66,77)(H,67,80)(H,68,83)(H,69,82)(H,70,79)(H,71,81)(H4,57,58,60);1H3,(H,3,4)/t36-,37-,38-,39-,40-,41-,42-,43-;/m0./s1

SMILES: CC(C)C[C@@H](C(=N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=NCC(=N)O)O)O)N=C(CN=C([C@H](Cc1ccc(cc1)O)N=C([C@H](CO)N=C([C@H](Cc1c[nH]c2ccccc12)N=C([C@H](Cc1cnc[nH]1)N=C([C@@H]1CCC(=N1)O)O)O)O)O)O)O.CC(=O)O

Synonyms:

• Gonadelin Acetate
• Luteinizing hormone-releasing factor (pig), acetate (salt)
• Cystorelin
• Fertiline
• Luprolite acetate
• Lutrelef
• Lutrepulse
• Synthetic luteinizing hormone-releasing factor acetate
• Luteinizing hormone-releasing factor (swine), acetate (salt)
• 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosylglycyl-L-leucyl-N~5~-(diaminomethylidene)-L-ornithyl-L-prolylglycinamide acetate (1:1)
• Gonadorelin Acetate/GnRH

GONADORELIN FOR NMR IDENTIFICATION CRS

CAS: 34973-08-5

GONADORELIN FOR NMR IDENTIFICATION CRS

Formula: C₅₅H₇₅N₁₇O₁₃

Molecular weight: 1182.29

Ref: 41-Y0001546

GONADORELIN CRS

CAS: 34973-08-5

GONADORELIN CRS

Color and Shape: Added

Ref: 41-G0525000

GONADORELIN FOR SYSTEM SUITABILITY A CRS

CAS: 34973-08-5

GONADORELIN FOR SYSTEM SUITABILITY A CRS

Ref: 41-Y0002318

Gonadorelin Acetate

CAS: 34973-08-5

Formula: C₅₅H₇₅N₁₇O₁₃

Purity: 95%~99%

Color and Shape: White to Off-white Powder

Molecular weight: 1182.29

Ref: BP-BPPG037

Gonadorelin Acetate

CAS: 34973-08-5

Applications Gonadorelin Acetate is used in various agricultural and biological studies. It was used in the study of ovulation synchronization in dairy cows.
References Pursley, J., et al.: Theriogenology, 44, 915 (1995).

Formula: C₅₅H₇₅N₁₇O₁₃·C₂H₄O₂

Color and Shape: Neat

Molecular weight: 1242.34

Ref: TR-G766713

Gonadorelin acetate

CAS: 34973-08-5

Gonadorelin acetate is a synthetic peptide agonist, which is an analog of the naturally occurring gonadotropin-releasing hormone (GnRH). It is derived from a synthetic process designed to mimic the structure and function of endogenous GnRH. Gonadorelin acetate functions by stimulating the anterior pituitary gland to release two critical hormones: luteinizing hormone (LH) and follicle-stimulating hormone (FSH). These hormones play a pivotal role in regulating reproductive processes, including ovulation and spermatogenesis.

Formula: C₅₅H₇₅N₁₇O₁₃·xC₂H₄O₂

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 1182.29

Ref: 3D-FG65032

Gonadorelin Acetate

CAS: 34973-08-5

Formula: C₅₇H₇₉N₁₇O₁₅

Molecular weight: 1242.36

Ref: ST-EA-CP-G90004