CAS 35000-38-5

(tert-Butoxycarbonylmethylene)triphenylphosphorane

Description:

(tert-Butoxycarbonylmethylene)triphenylphosphorane, commonly referred to as a phosphorane compound, is characterized by its unique structure that includes a triphenylphosphine moiety and a tert-butoxycarbonylmethylene group. This compound typically exhibits a high degree of stability due to the resonance stabilization provided by the triphenylphosphine, which is a well-known reagent in organic synthesis. The tert-butoxycarbonyl (Boc) group is often used as a protecting group for amines and can facilitate various reactions, including nucleophilic additions. The presence of the methylene group contributes to its reactivity, allowing it to participate in various organic transformations. Additionally, this compound is generally soluble in organic solvents, making it suitable for use in synthetic organic chemistry. Its applications may include use in the synthesis of complex organic molecules, particularly in the context of peptide synthesis and other areas where selective functionalization is required. As with many phosphoranes, care should be taken when handling due to potential reactivity and the need for proper storage conditions to maintain stability.

Formula: C₂₄H₂₅O₂P

InChI: InChI=1S/C24H25O2P/c1-24(2,3)26-23(25)19-27(20-13-7-4-8-14-20,21-15-9-5-10-16-21)22-17-11-6-12-18-22/h4-19H,1-3H3

InChI key: InChIKey=ZWZUFQPXYVYAFO-UHFFFAOYSA-N

SMILES: P(=CC(OC(C)(C)C)=O)(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3

Synonyms:

• (Triphenyl-λ⁵-phosphanylidene)acetic acid tert-butyl ester
• (Triphenylphosphoranylidene)acetic acid tert-butyl ester
• (tert-Butoxycarbonylmethylene)triphenylphosphoran
• (tert-Butoxycarbonylmethylene)triphenylphosphorane
• 1,1-Dimethylethyl (triphenylphosphoranylidene)acetate
• 1,1-Dimethylethyl 2-(triphenyl-λ5-phosphanylidene)acetate
• Acetic acid, (triphenylphosphoranylidene)-, 1,1-dimethylethyl ester
• Acetic acid, 2-(triphenylphosphoranylidene)-, 1,1-dimethylethyl ester
• NSC 82469
• Tert-Butyl (Triphenyl-Lambda~5~-Phosphanylidene)Acetate
• Triphenyl(tert-butoxycarbonylmethylene)phosphorane
• tert-Butyl (triphenylphosphoranylidene)acetate
• tert-Butyl (triphenylphosphoranylidene)acetate~(Carbo-tert-butoxymethylene)triphenylphosphorane
• tert-Butyl 2-(triphenylphosphaneylidene)acetate
• tert-Butyl 2-(triphenylphosphoranylidene)acetate

(tert-Butoxycarbonylmethylene)triphenylphosphorane, 98%

CAS: 35000-38-5

(tert-Butoxycarbonylmethylene)triphenylphosphorane is a chemical used in the synthesis of aldose reductase inhibitors, a podophyllotoxin derivative and tautomycin, a podophyllotoxin derivative and tautomycin. It Is also used in medicinal chemistry. This Thermo Scientific Chemicals brand product was

Formula: C₂₄H₂₅O₂P

Purity: 98%

Color and Shape: White to pale yellow, Crystals or powder or crystalline powder

Molecular weight: 376.44

Ref: 02-L15144

Tert-Butyl 2-(triphenylphosphoranylidene)acetate

CAS: 35000-38-5

Formula: C₂₄H₂₅O₂P

Purity: 95%

Color and Shape: Solid

Molecular weight: 376.4279

Ref: IN-DA0035MW

tert-Butyl (Triphenylphosphoranylidene)acetate

CAS: 35000-38-5

tert-Butyl (Triphenylphosphoranylidene)acetate

Formula: C₂₄H₂₅O₂P

Purity: 97%

Color and Shape: white to off white solid

Molecular weight: 376.43g/mol

Ref: 54-OR72608

tert-Butyl 2-(triphenylphosphoranylidene)acetate

CAS: 35000-38-5

tert-Butyl 2-(triphenylphosphoranylidene)acetate

Purity: 98%

Molecular weight: 376.43g/mol

Ref: 54-OR80124

tert-Butyl (Triphenylphosphoranylidene)acetate

CAS: 35000-38-5

Formula: C₂₄H₂₅O₂P

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 376.44

Ref: 3B-B3877

tert-Butyl 2-(triphenylphosphoranylidene)acetate

CAS: 35000-38-5

Formula: C₂₄H₂₅O₂P

Purity: 95%

Color and Shape: Solid

Molecular weight: 376.436

Ref: 10-F235005

(tert-​Butoxycarbonylmethyl​ene)​triphenylphosphorane

Controlled Product

CAS: 35000-38-5

Applications (tert-​Butoxycarbonylmethyl​ene)​triphenylphosphorane is a reactant used as a catalyst in the synthesis of indanols as well as α,​β-​unsatd. fatty acids.
References Loesche, A. et al.: Bioorg. Med Chem. Lett., 28, 3315 (2018); Panchal, H. et al.: Chem. Comm., 54, 12389 (2018);

Formula: C₂₄H₂₅O₂P

Color and Shape: Neat

Molecular weight: 376.43

Ref: TR-B943165