Ac-YVAD-FMK, with the CAS number 350021-87-3, is a synthetic peptide that serves as a selective inhibitor of caspase-1, an enzyme involved in the inflammatory response and apoptosis. This compound is characterized by its ability to covalently modify the active site of caspase-1, thereby inhibiting its activity and preventing the cleavage of pro-inflammatory cytokines such as IL-1β and IL-18. Ac-YVAD-FMK is often utilized in research to study the role of caspase-1 in various biological processes, including inflammation, cell death, and immune responses. The peptide structure includes an acetyl group at the N-terminus, which enhances its cell permeability, allowing it to effectively enter cells and exert its inhibitory effects. Due to its specificity for caspase-1, Ac-YVAD-FMK is valuable in elucidating the mechanisms of diseases associated with dysregulated inflammation, making it a useful tool in both basic and applied biomedical research.

Ac-YVAD-FMK

350021-87-3: Ac-YVAD-FMK, with the CAS number 350021-87-3, is a synthetic peptide that serves as a selective inhibitor of caspase-1, an enzyme involved in the inflammatory response and apoptosis. This compound is characterized by its ability to covalently modify the active site of caspase-1, thereby inhibiting its activity and preventing the cleavage of pro-inflammatory cytokines such as IL-1β and IL-18. Ac-YVAD-FMK is often utilized in research to study the role of caspase-1 in various biological processes, including inflammation, cell death, and immune responses. The peptide structure includes an acetyl group at the N-terminus, which enhances its cell permeability, allowing it to effectively enter cells and exert its inhibitory effects. Due to its specificity for caspase-1, Ac-YVAD-FMK is valuable in elucidating the mechanisms of diseases associated with dysregulated inflammation, making it a useful tool in both basic and applied biomedical research.

<p>[D-Trp8]-γ-MSH acetate(321351-81-9 free base)</p>

CAS 350021-87-3

Ac-YVAD-FMK

[D-Trp8]-γ-MSH acetate(321351-81-9 free base)

Ref: 54-BUP20323