CAS 35037-73-1

4-(Trifluoromethoxy)phenyl isocyanate

Description:

4-(Trifluoromethoxy)phenyl isocyanate is an organic compound characterized by the presence of an isocyanate functional group (-N=C=O) attached to a phenyl ring that is further substituted with a trifluoromethoxy group (-O-CF3). This compound typically appears as a colorless to pale yellow liquid or solid, depending on the temperature and purity. It is known for its reactivity, particularly in forming urethane linkages when reacting with alcohols or amines. The trifluoromethoxy group enhances the compound's lipophilicity and can influence its chemical stability and reactivity. Additionally, the presence of fluorine atoms contributes to its unique properties, such as increased electronegativity and potential applications in pharmaceuticals and agrochemicals. Due to the isocyanate functionality, it is important to handle this compound with care, as isocyanates are known to be toxic and can cause respiratory irritation. Proper safety measures should be employed when working with this substance in laboratory or industrial settings.

Formula: C₈H₄F₃NO₂

InChI: InChI=1S/C8H4F3NO2/c9-8(10,11)14-7-3-1-6(2-4-7)12-5-13/h1-4H

InChI key: InChIKey=LGPKFIGMLPDYEA-UHFFFAOYSA-N

SMILES: O(C(F)(F)F)C1=CC=C(N=C=O)C=C1

Synonyms:

• 1-Isocyanato-4-(Trifluoromethoxy)-Benzen
• 1-Isocyanato-4-(Trifluoromethoxy)Benzene
• 4-(Trifluoromethoxy)Phnyl Isocyanate
• 4-Trifluoromethoxy Phenylisocyanate
• 4-Trifluromethoxylphenylisocyanate
• Benzene, 1-isocyanato-4-(trifluoromethoxy)-
• Isocyanato-4-(trifluoromethoxy)benzene
• P-(Trifluoromethoxy)Phenyl Isocyanate
• 4-(Trifluoromethoxy) phenyl isocyanate
• 4-(Trifluoromethoxy)phenyl isocyanate

4-(Trifluoromethoxy)phenyl Isocyanate

CAS: 35037-73-1

Formula: C₈H₄F₃NO₂

Purity: >98.0%(GC)

Color and Shape: Colorless to Light yellow clear liquid

Molecular weight: 203.12

Ref: 3B-T2487

4-(Trifluoromethoxy)phenyl isocyanate, 97%

CAS: 35037-73-1

4-(Trifluoromethoxy)phenyl isocyanate is used as a synthetic intermediate for medicine This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / ite

Formula: C₈H₄F₃NO₂

Purity: 97%

Color and Shape: Clear colorless, Liquid

Molecular weight: 203.12

Ref: 02-B20033

4-(Trifluoromethoxy)phenyl isocyanate

CAS: 35037-73-1

Formula: C₈H₄F₃NO₂

Purity: 98%

Color and Shape: Liquid

Molecular weight: 203.1181

Ref: IN-DA0033U4

4-Trifluoromethoxyphenylisocyanate

CAS: 35037-73-1

Formula: C₈H₄F₃NO₂

Molecular weight: 203.12

Ref: 7W-GK0861

4-(Trifluoromethoxy)phenyl isocyanate

CAS: 35037-73-1

4-(Trifluoromethoxy)phenyl isocyanate

Formula: C₈H₄F₃NO₂

Purity: 95%

Color and Shape: clear. faint beige (with crystalline needles) liquid

Molecular weight: 203.12g/mol

Ref: 54-PC4489

4-(Trifluoromethoxy)phenyl isocyanate

CAS: 35037-73-1

4-(Trifluoromethoxy)phenyl isocyanate

Purity: 98%

Color and Shape: Almost Colourless Liquid

Molecular weight: 203.12g/mol

Ref: 54-PC7439Q

4-(Trifluoromethoxy)phenyl isocyanate

CAS: 35037-73-1

4-(Trifluoromethoxy)phenyl isocyanate (4-TFPC) is a potent antagonist of the platelet P2Y12 receptor. It inhibits platelet aggregation and adhesion, as well as prevents the formation of blood clots. 4-TFPC has a low molecular weight and can be administered orally. It also has been shown to increase insulin sensitivity and reduce blood glucose levels in mice with type 2 diabetes. This antiplatelet agent binds to receptors on the surface of platelets, preventing activation. 4-TFPC is also an inhibitor of protein kinase C and phosphodiesterases, which are enzymes that regulate cell signalling pathways. In vitro studies have shown that 4-TFPC inhibits cycloheptyl (CPH)-induced aggregation in human platelets in a dose-dependent manner with an IC50 value of 0.5 μM.END>

Formula: C₈H₄F₃NO₂

Purity: Min. 95%

Color and Shape: Colorless Clear Liquid

Molecular weight: 203.12 g/mol

Ref: 3D-FT00399

1-Isocyanato-4-trifluoromethoxy-benzene

CAS: 35037-73-1

Formula: C₈H₄F₃NO₂

Purity: 98%

Color and Shape: Liquid

Molecular weight: 203.12

Ref: 10-F034227