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CAS 35048-47-6

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Estradiol 6-(O-carboxymethyl)oxime

Description:
Estradiol 6-(O-carboxymethyl)oxime is a derivative of estradiol, a potent estrogen hormone involved in various physiological processes. This compound features a carboxymethyl oxime functional group at the 6-position of the estradiol structure, which may influence its biological activity and solubility. Typically, such modifications can enhance the compound's pharmacokinetic properties, potentially improving its stability and bioavailability. Estradiol itself is known for its role in the regulation of the menstrual cycle, reproductive system, and secondary sexual characteristics. The oxime group may also impart unique reactivity and interaction capabilities with biological targets. As with many steroid derivatives, the compound's characteristics, including its melting point, solubility, and reactivity, can vary based on the specific structural modifications. Research into this compound may focus on its potential therapeutic applications, particularly in hormone replacement therapy or as a part of treatments for estrogen-related conditions. However, detailed studies would be necessary to fully elucidate its properties and biological effects.
Formula:C20H25NO5
InChI:InChI=1S/C20H25NO5/c1-20-7-6-13-12-3-2-11(22)8-15(12)17(21-26-10-19(24)25)9-14(13)16(20)4-5-18(20)23/h2-3,8,13-14,16,18,22-23H,4-7,9-10H2,1H3,(H,24,25)/t13-,14-,16+,18+,20+/m1/s1
InChI key:InChIKey=AWARIMYXKAIIGO-XQRBHQRSSA-N
SMILES:C[C@@]12[C@]([C@]3([C@@](C=4C(C(=NOCC(O)=O)C3)=CC(O)=CC4)(CC1)[H])[H])(CC[C@@H]2O)[H]
Synonyms:
  • ({[(6E,8ξ,9ξ,14ξ,17β)-3,17-dihydroxyestra-1,3,5(10)-trien-6-ylidene]amino}oxy)acetic acid
  • 17β-Estradiol 6-(O-carboxymethyl)oxime
  • 2-[[[(17β)-3,17-Dihydroxyestra-1,3,5(10)-trien-6-ylidene]amino]oxy]acetic acid
  • 6-Oxo-17β-estradiol 6-[O-(carboxymethyl)oxime]
  • 6-Oxoestradiol (carboxymethyl)oxime
  • 6-ketoestradiol 6-(O-carboxymethyl)-*oxime
  • Acetic acid, 2-[[[(17β)-3,17-dihydroxyestra-1,3,5(10)-trien-6-ylidene]amino]oxy]-
  • Acetic acid, [[[(17β)-3,17-dihydroxyestra-1,3,5(10)-trien-6-ylidene]amino]oxy]-
  • Estradiol 6-(O-carboxymethyl)oxime
  • Estradiol 6-carboxymethyloxime
  • See more synonyms
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Found 3 products.
  • β-Estradiol-6-one 6-(O-carboxymethyloxime)
    Glentham
    + Info

    β-Estradiol-6-one 6-(O-carboxymethyloxime)

    CAS:
    Formula:C20H25NO5
    Purity:≥ 98.0%
    Color and Shape:White to off-white powder
    Molecular weight:359.42

    Ref: 7W-GL1881

    ne
    To inquire
  • β-Estradiol-6-one 6-(O-carboxymethyloxime)
    Targetmol
    + Info

    β-Estradiol-6-one 6-(O-carboxymethyloxime)

    CAS:
    β-Estradiol-6-one 6-(O-carboxymethyloxime) is an alkyl chain-based PROTAC linker utilized for PROTAC synthesis[1].
    Formula:C20H25NO5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:359.422

    Ref: TM-T18877

  • b-Estradiol-6-one 6-(O-carboxymethyloxime)
    TRC
    + Info

    b-Estradiol-6-one 6-(O-carboxymethyloxime)

    Controlled Product
    CAS:
    <p>Applications β-Estradiol-6-one 6-(O-carboxymethyloxime) was shown to exhibit regulatory activities towards the expression of leptin, a protein hormone that coordinate appetite/hunger and metabolism.β-Estradiol-6-one 6-(O-carboxymethyloxime) was shown to control the secretion of leptin via membrane associated estrogen receptor alpha in human placental cells.<br>References Gambino, Y.P., et al.: Molec. Cell. Res., 1823, 900 (2012); Somjen, D., et al.: J. Steroid. Biochem. Molec. Biol., 113, 171 (2009); Arreguin-Arevaloand, J.A.. et al.: Biol. Reproduct., 74, 202 (2006);<br></p>
    Formula:C20H25NO5
    Color and Shape:Neat
    Molecular weight:359.42

    Ref: TR-E888080

    25mg
    323.00€
    100mg
    1,061.00€
    250mg
    2,084.00€