CAS 35059-50-8

tert-butyl diazoacetate

Description:

Tert-butyl diazoacetate is an organic compound characterized by its diazo functional group, which is known for its reactivity in various chemical reactions, particularly in the formation of carbon-carbon bonds. It has a tert-butyl group, which contributes to its steric bulk and influences its reactivity. The compound is typically a colorless to pale yellow liquid and is soluble in organic solvents. Its structure includes a diazo group (-N=N-) attached to an acetate moiety, making it a useful reagent in organic synthesis, especially in the generation of carbenes. Tert-butyl diazoacetate is often employed in cyclopropanation reactions and other transformations that involve the generation of reactive intermediates. Due to the presence of the diazo group, it can be sensitive to heat and light, necessitating careful handling and storage under inert atmospheres. Safety precautions are essential when working with this compound, as diazo compounds can be hazardous and potentially explosive under certain conditions.

Formula: C₆H₁₀N₂O₂

InChI: InChI=1/C6H10N2O2/c1-6(2,3)10-5(9)4-8-7/h4H,1-3H3

SMILES: CC(C)(C)OC(=O)C=[N+]=[NH-]

Synonyms:

• 1-Tert-Butoxy-2-Diazonioethenolate

tert-Butyl Diazoacetate

CAS: 35059-50-8

Formula: C₆H₁₀N₂O₂

Purity: 95%

Color and Shape: Liquid

Molecular weight: 142.1558

Ref: IN-DA003UKM

tert-Butyl 2-diazoacetate

CAS: 35059-50-8

tert-Butyl 2-diazoacetate

Formula: C₆H₁₀N₂O₂

Purity: 96%

Color and Shape: clear. yellow liquid

Molecular weight: 142.16g/mol

Ref: 54-OR73958

tert-Butyl 2-diazoacetate

CAS: 35059-50-8

Purity: 95%

Color and Shape: Liquid, Oil

Molecular weight: 142.16

Ref: 10-F448618

tert-Butyl Diazoacetate, 85%

Controlled Product

CAS: 35059-50-8

Applications An intermediate in the production of Zolpidem metabolites
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Klupsch, F., et al.: Chem. Pharm. Bull., 54, 1318 (2006), Epple, R., et al.: Bioorg. Med. Chem. Lett., 16, 5488 (2006),

Formula: C₆H₁₀N₂O₂

Purity: 85%

Color and Shape: Neat

Molecular weight: 142.16

Ref: TR-B691035

tert-Butyl diazoacetate

CAS: 35059-50-8

Tert-Butyl diazoacetate is an ethyl diazoacetate that undergoes a copper-catalyzed alkylation with 4-acetamidobenzene sulfonyl azide. The reaction rate is dependent on the concentration of chloride, which is the only byproduct. This compound has been used in asymmetric synthesis of 4-formylbenzenesulfonyl azide and has shown to be a useful tool for organic chemists due to its size-exclusion chromatography properties. Tert-Butyl diazoacetate also reacts with styrene to produce unsaturated ketones such as salicylaldehyde, which can be further modified. Tert-Butyl diazoacetate is also an important bioactive molecule because it can be isolated from natural sources like horseradish or soybean sprouts.

Formula: C₆H₁₀N₂O₂

Purity: Min. 95%

Molecular weight: 142.16 g/mol

Ref: 3D-FT59573