CAS 350992-10-8

Bifeprunox

Description:

Bifeprunox is an atypical antipsychotic compound primarily investigated for the treatment of schizophrenia and other psychiatric disorders. It is characterized by its unique chemical structure, which includes a piperazine moiety and a phenyl group, contributing to its pharmacological profile. Bifeprunox acts as a partial agonist at dopamine D2 receptors and has affinity for serotonin receptors, which may help in modulating neurotransmitter activity in the brain. This dual action is thought to provide therapeutic benefits while potentially minimizing some of the side effects commonly associated with traditional antipsychotics. The substance has been studied for its efficacy in improving symptoms of psychosis and cognitive deficits. Additionally, Bifeprunox has shown a favorable side effect profile in clinical trials, with lower incidences of extrapyramidal symptoms compared to older antipsychotic medications. However, as of the latest updates, it has not received widespread approval for clinical use, and ongoing research continues to evaluate its safety and effectiveness in various populations.

Formula: C₂₄H₂₃N₃O₂

InChI: InChI=1/C24H23N3O2/c28-24-25-21-10-5-11-22(23(21)29-24)27-14-12-26(13-15-27)17-18-6-4-9-20(16-18)19-7-2-1-3-8-19/h1-11,16H,12-15,17H2,(H,25,28)

InChI key: InChIKey=CYGODHVAJQTCBG-UHFFFAOYSA-N

SMILES: O=C1OC2=C(C=CC=C2N1)N3CCN(CC4=CC(=CC=C4)C5=CC=CC=C5)CC3

Synonyms:

• 2(3H)-benzoxazolone, 7-[4-([1,1'-biphenyl]-3-ylmethyl)-1-piperazinyl]-
• 7-[4-([1,1′-Biphenyl]-3-ylmethyl)-1-piperazinyl]-2(3H)-benzoxazolone
• Bifeprunox
• 7-(4-([1,1,-biphenyl]-3-ylmethyl)piperazin-1-yl)benzo[d]oxazol-2(3H)-one
• 7-[4-[(3-phenylphenyl)methyl]-1-piperazinyl]-3H-1,3-benzoxazol-2-one
• 7-[4-[(3-phenylphenyl)methyl]piperazin-1-yl]-3H-benzooxazol-2-one

Bifeprunox

CAS: 350992-10-8

Formula: C₂₄H₂₃N₃O₂

Molecular weight: 385.47

Ref: 4Z-B-212001

Bifeprunox

CAS: 350992-10-8

Bifeprunox is a small-molecule drug that blocks the activity of the GABA receptor. It has pharmacological and biological effects in various systems, including inhibition of GABA binding to its receptors, activation of the GABA receptor, modulation of cell proliferation and migration, and modulation of protein interactions. Bifeprunox binds to an allosteric site on the GABA receptor and modulates the binding affinity for GABA at this site. It is used as a research tool for studying neurotransmitter receptors.

Formula: C₂₄H₂₃N₃O₂

Purity: Min. 95%

Molecular weight: 385.5 g/mol

Ref: 3D-APA99210

Bifeprunox

CAS: 350992-10-8

Bifeprunox: potent antipsychotic, partial agonist at D2-like/5-HT1A receptors; treats schizophrenia.

Formula: C₂₄H₂₃N₃O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 385.46

Ref: TM-T10542