CAS 350992-13-1

7-[4-(Biphenyl-3-ylmethyl)piperazin-1-yl]benzoxazol-2(3H)-one methanesulfonate

Description:

7-[4-(Biphenyl-3-ylmethyl)piperazin-1-yl]benzoxazol-2(3H)-one methanesulfonate, with the CAS number 350992-13-1, is a synthetic organic compound characterized by its complex structure, which includes a benzoxazole moiety and a piperazine ring. This compound typically exhibits properties such as solubility in polar solvents, which is common for many sulfonate derivatives, and may demonstrate biological activity due to its piperazine and biphenyl components. The presence of the methanesulfonate group suggests it may have good stability and solubility in aqueous environments, making it suitable for various applications in medicinal chemistry. Its structure indicates potential interactions with biological targets, which could be explored for therapeutic purposes. Additionally, the compound's unique arrangement of functional groups may contribute to its pharmacokinetic properties, influencing absorption, distribution, metabolism, and excretion (ADME) characteristics. Overall, this compound represents a class of molecules that may be of interest in drug development and research.

Formula: C₂₅H₂₇N₃O₅S

InChI: InChI=1/C24H23N3O2.CH4O3S/c28-24-25-21-10-5-11-22(23(21)29-24)27-14-12-26(13-15-27)17-18-6-4-9-20(16-18)19-7-2-1-3-8-19;1-5(2,3)4/h1-11,16H,12-15,17H2,(H,25,28);1H3,(H,2,3,4)

SMILES: c1ccc(cc1)c1cccc(c1)CN1CCN(CC1)c1cccc2c1oc(n2)O.CS(=O)(=O)O

Synonyms:

• Bifeprunox mesilate
• Du-127090
• 7-[4-(biphenyl-3-ylmethyl)piperazin-1-yl]-1,3-benzoxazol-2(3H)-one methanesulfonate

Bifeprunox Mesylate

Controlled Product

CAS: 350992-13-1

Applications Used as an antipsychotic compound. Activates the serotonin 5-hydroxytryptamine (5-HT)1A receptor.
References Wolf, W., et al.: Curr. Opin. Invest. Drugs, 4, 72 (2003), Assie, M.B., et al.: J. Pharmacol. Exp. Ther., 315(1), 265 (2005)

Formula: C₂₄H₂₃N₃O₂·CH₄O₃S

Color and Shape: Neat

Molecular weight: 481.56

Ref: TR-B383200

Bifeprunox Mesylate

CAS: 350992-13-1

Bifeprunox: partial dopamine/serotonin agonist for schizophrenia; suppresses VTA neurons via D2; affects rat nicotine-seeking.

Formula: C₂₅H₂₇N₃O₅S

Purity: 98%

Color and Shape: Solid

Molecular weight: 481.56

Ref: TM-T26807