CAS 351-35-9

[3-(Trifluoromethyl)phenyl]acetic acid

Description:

[3-(Trifluoromethyl)phenyl]acetic acid, with the CAS number 351-35-9, is an aromatic carboxylic acid characterized by the presence of a trifluoromethyl group attached to a phenyl ring. This compound typically exhibits a white to off-white crystalline solid form and is known for its relatively high melting point. The trifluoromethyl group contributes to its unique electronic properties, enhancing its lipophilicity and potentially influencing its reactivity and biological activity. It is soluble in organic solvents such as ethanol and acetone but has limited solubility in water due to its hydrophobic characteristics. The compound is often utilized in organic synthesis and pharmaceutical research, serving as an intermediate in the production of various biologically active compounds. Its chemical structure allows for potential applications in agrochemicals and materials science as well. Safety data indicates that, like many fluorinated compounds, it should be handled with care due to potential toxicity and environmental concerns.

Formula: C₉H₇F₃O₂

InChI: InChI=1S/C9H7F3O2/c10-9(11,12)7-3-1-2-6(4-7)5-8(13)14/h1-4H,5H2,(H,13,14)

InChI key: InChIKey=BLXXCCIBGGBDHI-UHFFFAOYSA-N

SMILES: C(C(O)=O)C1=CC(C(F)(F)F)=CC=C1

Synonyms:

• (Alpha,Alpha,Alpha-Trifluoro-M-Tolyl)Acetic Acid
• (m-Trifluoromethylphenyl)acetic acid
• (α,α,α-Trifluoro-m-tolyl)acetic acid
• 2-[3-(Trifluoromethyl)phenyl]acetic acid
• 3-(Trifluoromethyl)benzeneacetic acid
• 3-Trifluoromethyl Phenylacetic Acid
• 3-Trifluoromethylbenzeneacetic acid
• Acetic acid, (α,α,α-trifluoro-m-tolyl)-
• Benzeneacetic acid, 3-(trifluoromethyl)-
• [3-(Trifluoromethyl)Phenyl]Acetate
• [3-(Trifluoromethyl)Phenyl]Acetic Acid

3-(Trifluoromethyl)phenylacetic acid, 96%

CAS: 351-35-9

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₉H₇F₃O₂

Purity: 96%

Color and Shape: Crystals or powder or crystalline powder or lumps or chunks or fused solid, White to cream to pale brown

Molecular weight: 204.15

Ref: 02-L10960

3-(Trifluoromethyl)phenylacetic acid

CAS: 351-35-9

Formula: C₉H₇F₃O₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 204.1459

Ref: IN-DA003547

3-Trifluoromethylphenylacetic acid

CAS: 351-35-9

Formula: C₉H₇F₃O₂

Molecular weight: 204.15

Ref: 7W-GK9387

3-(Trifluoromethyl)phenylacetic Acid

CAS: 351-35-9

Formula: C₉H₇F₃O₂

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 204.15

Ref: 3B-T1662

3-(Trifluoromethyl)phenylacetic acid

CAS: 351-35-9

3-(Trifluoromethyl)phenylacetic acid

Formula: C₉H₇F₃O₂

Purity: 98%

Color and Shape: white crystals

Molecular weight: 204.15g/mol

Ref: 54-PC7699

3-(Trifluoromethyl)phenylacetic acid

CAS: 351-35-9

Formula: C₉H₇F₃O₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 204.148

Ref: 10-F002139

3-(Trifluoromethyl)phenylacetic acid

CAS: 351-35-9

3-(Trifluoromethyl)phenylacetic acid is an isoquinoline alkaloid that has been found to have anti-inflammatory properties. It was shown to inhibit TNF-α production in mice with colitis, reducing the severity of the disease. 3-(Trifluoromethyl)phenylacetic acid can be administered orally, and it is metabolized reductively by dihydroisoquinoline reductase enzymes. The drug's pharmacokinetics are not well understood, but it is thought to be a substrate for CYP3A4 and P-glycoprotein. 3-(Trifluoromethyl)phenylacetic acid has been studied as a potential antiviral agent and systemic inflammatory response inhibitor.

Formula: C₉H₇F₃O₂

Purity: Min. 95%

Molecular weight: 204.15 g/mol

Ref: 3D-FT46007