CAS 351-83-7

N-(4-Fluorophenyl)acetamide

Description:

N-(4-Fluorophenyl)acetamide, with the CAS number 351-83-7, is an organic compound characterized by its amide functional group. It features a fluorinated aromatic ring, specifically a para-fluorophenyl group, attached to an acetamide moiety. This compound typically appears as a white to off-white solid and is soluble in organic solvents such as ethanol and acetone, but has limited solubility in water. The presence of the fluorine atom can influence its chemical reactivity and biological activity, often enhancing lipophilicity and altering pharmacokinetic properties. N-(4-Fluorophenyl)acetamide is of interest in medicinal chemistry and may serve as a building block in the synthesis of pharmaceuticals or agrochemicals. Its properties, including melting point, boiling point, and specific reactivity, can vary based on the conditions and purity of the sample. As with many amides, it may exhibit hydrogen bonding capabilities, influencing its interactions in biological systems. Safety data should be consulted for handling and exposure guidelines, as with any chemical substance.

Formula: C₈H₈FNO

InChI: InChI=1/C8H8FNO/c1-6(11)10-8-4-2-7(9)3-5-8/h2-5H,1H3,(H,10,11)

InChI key: InChIKey=JHEFOJNPLXSWNZ-UHFFFAOYSA-N

SMILES: N(C(C)=O)C1=CC=C(F)C=C1

Synonyms:

• 4-Acetylamino-1-fluorobenzene
• Acetamide, N-(4-fluorophenyl)-
• Acetamide, N-(4-fluorophenyl)- (9CI)
• Acetanilide, 4'-fluoro-
• Ai3-52222
• Brn 2208090
• N-(4-Fluorophenyl)acetamide
• N-Acetyl-4-fluoroaniline
• N-p-Fluorophenylacetamide
• Nsc 10349
• p-Fluoroacetanilide
• 4-12-00-01107 (Beilstein Handbook Reference)
• 4-Fluoroacetanilide
• 1-ACETAMIDO-4-FLUOROBENZENE
• 4-Fluoroacetanilide,98%
• 4'-Fluoroacetanilide, 99+%
• n-(4-fluorophenyl)-acetamid
• 4’-fluoro-acetanilid
• 4-Fluorophenyl acetamide
• N-(4-Fluorophenyl)acetanilide

4'-Fluoroacetanilide

CAS: 351-83-7

Formula: C₈H₈FNO

Purity: >98.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 153.16

Ref: 3B-F0521

4-Fluoroacetanilide

CAS: 351-83-7

Formula: C₈H₈FNO

Purity: 97%

Color and Shape: Solid

Molecular weight: 153.1536

Ref: IN-DA003LES

4''-Fluoroacetanilide

CAS: 351-83-7

Formula: C₈H₈FNO

Molecular weight: 153.16

Ref: 7W-GK9395

4'-Fluoroacetanilide

CAS: 351-83-7

4'-Fluoroacetanilide

Formula: C₈H₈FNO

Purity: 98%

Color and Shape: white to off-white solid

Molecular weight: 153.15g/mol

Ref: 54-PC3340

N-(4-Fluorophenyl)acetamide

CAS: 351-83-7

4-Fluorophenylacetic acid is a synthetic organic compound that has been used as a model system for the study of the reaction between hydrogen sulfate and hydrogen. 4-Fluorophenylacetic acid is a fluorinated analog of acetamide, which can be synthesized from sodium borohydride and hydrogen fluoride. It has been shown to inhibit the growth of Mycobacterium tuberculosis in an on-line assay and is also active against Mycobacterium avium complex. 4-Fluorophenylacetic acid also inhibits rat liver microsomes with a second order rate constant of 0.0006 M−1 s−1 at pH 7.4 and 37 °C (pH and temperature not specified). The biological properties of 4-fluorophenylacetic acid are not well understood, but it may bind to hydrophobic regions on proteins or DNA through hydrogen bonding interactions.

Formula: C₈H₈FNO

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 153.15 g/mol

Ref: 3D-FF12167

4′-Fluoroacetanilide

CAS: 351-83-7

Formula: C₈H₈FNO

Purity: 97%

Color and Shape: Solid

Molecular weight: 153.156

Ref: 10-F003844