CAS 35109-88-7

2-Iodoadenosine

Description:

2-Iodoadenosine is a modified nucleoside that features an iodine atom substituted at the 2-position of the adenine base. This compound is characterized by its structural similarity to adenosine, which consists of a ribose sugar linked to an adenine base. The introduction of the iodine atom can influence the compound's biological activity, stability, and interaction with various enzymes and receptors. 2-Iodoadenosine is often studied for its potential roles in cellular signaling and as a tool in biochemical research, particularly in the context of purinergic signaling pathways. It may exhibit unique pharmacological properties compared to its unmodified counterpart, adenosine, and can be utilized in various experimental applications, including studies on receptor binding and cellular uptake. Additionally, the presence of the iodine atom can enhance the compound's visibility in imaging studies. Overall, 2-Iodoadenosine serves as an important compound in the field of medicinal chemistry and biochemistry, contributing to our understanding of nucleoside function and signaling mechanisms.

Formula: C₁₀H₁₂IN₅O₄

InChI: InChI=1/C10H12IN5O4/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15)/t3-,5-,6-,9-/m1/s1

SMILES: C([C@@H]1[C@H]([C@H]([C@H](n2cnc3c(N)nc(I)nc23)O1)O)O)O

Synonyms:

• Adenosine, 2-iodo-

2-Iodoadenosine

CAS: 35109-88-7

Formula: C₁₀H₁₂IN₅O₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 393.1379

Ref: IN-DA00329U

2-Iodoadenosine

CAS: 35109-88-7

2-Iodoadenosine

Purity: 98%

Molecular weight: 393.14g/mol

Ref: 54-OR310610

2-Iodo adenosine

CAS: 35109-88-7

Formula: C₁₀H₁₂IN₅O₄

Molecular weight: 393.14

Ref: 7W-GC8367

2-Iodoadenosine

CAS: 35109-88-7

Formula: C₁₀H₁₂IN₅O₄

Purity: >98.0%(HPLC)(N)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 393.14

Ref: 3B-I0759

2-Iodoadenosine

CAS: 35109-88-7

Nucleosides Derivatives –Halo-nucleosides; Scaffolds and Templates

Formula: C₁₀H₁₂IN₅O₄

Color and Shape: Solid

Molecular weight: 393.14

Ref: TM-TNU0156

2-Iodoadenosine

CAS: 35109-88-7

2-Iodoadenosine is a chemical compound that is produced from the oxidation of uridine. It is used in the synthesis of peptides, which are important for biological processes like signal transduction and cell growth. 2-Iodoadenosine can be made by coupling other molecules to an adenosine molecule. This process involves a cross-coupling reaction with palladium catalysts or hydroxylation reactions with sodium borohydride. The resulting product has been shown to have anticancer and anti-microbial activities against protozoan parasites and cyclic peptide structures.

Formula: C₁₀H₁₂IN₅O₄

Purity: Min. 97 Area-%

Color and Shape: Powder

Molecular weight: 393.14 g/mol

Ref: 3D-NI04749

2-Iodoadenosine

CAS: 35109-88-7

Formula: C₁₀H₁₂IN₅O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 393.141

Ref: 10-F224614

2-Iodo Adenosine35109-88-7

Controlled Product

CAS: 35109-88-7

Applications An intermediate in the synthesis of isoguanosine (crotonoside or 2-hydroxyadenosine), a naturally occuring nucleoside analogue of guanosine. Isoguanosine is incorporated into mammalian but not bacterial nucleic acids, stimulates the accumulation of cyclic AMP in the brain, and is an inhibitor of IMP:pyrophosphorylase.
References Lowry, B.A., et al.: J. Biol. Chem., 197, 591 (1952), Huang, M., et al.: J. Med. Chem., 15, 462 (1972), Hagen, C., et al.: Biochem. Biophys. Acta, 293, 105 (1973),

Formula: C₁₀H₁₂IN₅O₄

Color and Shape: Neat

Molecular weight: 393.14

Ref: TR-I686000