CAS 35115-60-7

angiotensin-converting enzyme inhibitor

Description:

Angiotensin-converting enzyme (ACE) inhibitors are a class of medications primarily used to treat hypertension and heart failure. The specific compound associated with the CAS number 35115-60-7 is a synthetic molecule that functions by inhibiting the activity of the angiotensin-converting enzyme, which plays a crucial role in the renin-angiotensin-aldosterone system (RAAS). By blocking this enzyme, ACE inhibitors prevent the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor, leading to vasodilation and reduced blood pressure. These compounds are characterized by their ability to improve cardiac output and reduce the workload on the heart. Additionally, they may have protective effects on the kidneys, particularly in diabetic patients. Common side effects can include cough, elevated potassium levels, and, in rare cases, angioedema. Overall, ACE inhibitors are an essential therapeutic option in managing cardiovascular diseases and are often prescribed alongside other medications for optimal patient outcomes.

Formula: C₅₃H₇₆N₁₄O₁₂

InChI: InChI=1/C53H76N14O12/c1-3-29(2)43(51(77)66-25-9-16-39(66)50(76)67-26-10-17-40(67)52(78)79)63-45(71)34(18-20-41(54)68)60-46(72)37-14-7-23-64(37)48(74)35(13-6-22-57-53(55)56)61-47(73)38-15-8-24-65(38)49(75)36(62-44(70)33-19-21-42(69)59-33)27-30-28-58-32-12-5-4-11-31(30)32/h4-5,11-12,28-29,33-40,43,58H,3,6-10,13-27H2,1-2H3,(H2,54,68)(H,59,69)(H,60,72)(H,61,73)(H,62,70)(H,63,71)(H,78,79)(H4,55,56,57)/t29-,33-,34-,35-,36-,37-,38-,39-,40-,43-/m0/s1

SMILES: CC[C@H](C)[C@@H](C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)O)N=C([C@H](CCC(=N)O)N=C([C@@H]1CCCN1C(=O)[C@H](CCCNC(=N)N)N=C([C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]c2ccccc12)N=C([C@@H]1CCC(=N1)O)O)O)O)O

Synonyms:

• (S)-1-((S)-1-((2S,3S)-2-((S)-2-((S)-1-((S)-2-((S)-1-((S)-3-(1H-Indol-3-Yl)-2-((S)-5-Oxopyrrolidine-2-Carboxamido)Propanoyl)Pyrrolidine-2-Carboxamido)-5-Guanidinopentanoyl)Pyrrolidine-2-Carboxamido)-5-

BPP 9a

CAS: 35115-60-7

A nonapeptide originally isolated from the venom of the Brazilian pit viper Bothrops jararaca. Teprotide inhibits angiotensin-converting enzyme (ACE) in vitro and in vivo.

Formula: C₅₃H₇₆N₁₄O₁₂

Purity: 98.3%

Color and Shape: Whitish Lyophilisate

Molecular weight: 1101.27

Ref: 01-4030395

Teprotide

CAS: 35115-60-7

Teprotide is an angiotensin-converting enzyme (ACE) inhibitor used to study hypertensive [1].

Formula: C₅₃H₇₆N₁₄O₁₂

Color and Shape: Solid

Molecular weight: 1101.26

Ref: TM-TP2636

BPP 9a Pyr-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro-OH

CAS: 35115-60-7

BPP 9a is an enzyme inhibitor that binds to the active site of angiotensin-converting enzyme (ACE) and blocks its activity. It is a nonsteroidal anti-inflammatory drug that has been shown to be effective in reducing inflammation and pain associated with arthritis, osteoarthritis, gout, and menstrual cramps. BPP 9a has also been shown to reduce blood pressure in a dose-dependent manner, which may be due to its ability to inhibit the synthesis of angiotensin II from angiotensin I. This inhibition may lead to decreased vascular tone and blood pressure. BPP 9a has also been shown to have beneficial effects on bowel disease and polymerase chain reaction (PCR) analysis of DNA.

Formula: C₅₃H₇₆N₁₄O₁₂

Purity: Min. 95%

Molecular weight: 1,101.26 g/mol

Ref: 3D-FB108627

BPP 9A

CAS: 35115-60-7

Formula: C₅₃H₇₆N₁₄O₁₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 1101.2571

Ref: IN-DA00BYSW