CAS 351227-64-0

4-[2-[(1R,2R)-2-(2,4-Difluorophenyl)-1-methyl-2-[(phosphonooxy)methoxy]-3-(1H-1,2,4-triazol-1-yl)propyl]-4-thiazolyl]benzonitrile

Description:

The chemical substance known as 4-[2-[(1R,2R)-2-(2,4-Difluorophenyl)-1-methyl-2-[(phosphonooxy)methoxy]-3-(1H-1,2,4-triazol-1-yl)propyl]-4-thiazolyl]benzonitrile, with the CAS number 351227-64-0, is a complex organic compound characterized by its multi-functional structure. It features a benzonitrile core, which is substituted with a thiazole moiety and a triazole group, indicating potential biological activity. The presence of a phosphonooxy group suggests that it may exhibit properties related to phosphonate chemistry, which is often associated with herbicidal or antimicrobial activities. The difluorophenyl group may enhance lipophilicity and biological activity. This compound is likely to be of interest in pharmaceutical research, particularly in the development of new therapeutic agents. Its intricate structure implies that it may interact with various biological targets, making it a candidate for further investigation in medicinal chemistry. As with many such compounds, understanding its solubility, stability, and reactivity will be crucial for its application in drug development or agrochemical formulations.

Formula: C₂₃H₂₀F₂N₅O₅PS

InChI: InChI=1S/C23H20F2N5O5PS/c1-15(22-29-21(10-37-22)17-4-2-16(9-26)3-5-17)23(11-30-13-27-12-28-30,34-14-35-36(31,32)33)19-7-6-18(24)8-20(19)25/h2-8,10,12-13,15H,11,14H2,1H3,(H2,31,32,33)/t15-,23+/m0/s1

InChI key: InChIKey=SYTNEMZCCLUTNX-NPMXOYFQSA-N

SMILES: [C@@]([C@@H](C)C1=NC(=CS1)C2=CC=C(C#N)C=C2)(CN3C=NC=N3)(OCOP(=O)(O)O)C4=C(F)C=C(F)C=C4

Synonyms:

• E 1224
• Fosravuconazole
• 4-[2-[(1R,2R)-2-(2,4-Difluorophenyl)-1-methyl-2-[(phosphonooxy)methoxy]-3-(1H-1,2,4-triazol-1-yl)propyl]-4-thiazolyl]benzonitrile
• Benzonitrile, 4-[2-[(1R,2R)-2-(2,4-difluorophenyl)-1-methyl-2-[(phosphonooxy)methoxy]-3-(1H-1,2,4-triazol-1-yl)propyl]-4-thiazolyl]-
• Fosravuconazole (Synonyms: BMS-379224
• SYTNEMZCCLUTNX-NPMXOYFQSA-N
• BMS-379224

Fosravuconazole

CAS: 351227-64-0

Fosravuconazole is an antifungal agent, classified as a triazole antifungal, which is developed from a synthetic chemical source. It operates as a prodrug of ravuconazole, meaning that after administration, fosravuconazole is converted into its active form in the body. This conversion enhances the absorption and bioavailability of the drug, providing improved treatment efficacy against fungal infections.

Formula: C₂₃H₂₀F₂N₅O₅PS

Purity: Min. 95%

Molecular weight: 547.5 g/mol

Ref: 3D-BPA22764

Fosravuconazole

CAS: 351227-64-0

Fosravuconazole is a ravuconazole prodrug. It has antifungal activity.

Formula: C₂₃H₂₀F₂N₅O₅PS

Purity: 98%

Color and Shape: Solid

Molecular weight: 547.47

Ref: TM-T15342