Daptomycin is a cyclic lipopeptide antibiotic primarily used to treat infections caused by Gram-positive bacteria, including those resistant to other antibiotics. The compound is characterized by its unique structure, which includes a fatty acid tail that enhances its membrane-targeting properties. Daptomycin works by disrupting bacterial cell membrane integrity, leading to cell death. Its mechanism of action involves calcium-dependent binding to the bacterial membrane, which triggers the formation of pores and ultimately results in the loss of essential ions and metabolites. The specific chemical structure of daptomycin includes a complex arrangement of amino acids, contributing to its stability and efficacy. It is typically administered intravenously and is known for its effectiveness against serious infections such as endocarditis and skin infections. Daptomycin is generally well-tolerated, although it may cause side effects such as muscle pain or weakness. Its use is often reserved for cases where other treatments are ineffective, particularly in the context of antibiotic resistance.

Daptomycin, 1-[(αS)-2-amino-γ-oxo-α-[(1-oxodecyl)amino]benzenebutanoic acid]-

351499-29-1: Daptomycin is a cyclic lipopeptide antibiotic primarily used to treat infections caused by Gram-positive bacteria, including those resistant to other antibiotics. The compound is characterized by its unique structure, which includes a fatty acid tail that enhances its membrane-targeting properties. Daptomycin works by disrupting bacterial cell membrane integrity, leading to cell death. Its mechanism of action involves calcium-dependent binding to the bacterial membrane, which triggers the formation of pores and ultimately results in the loss of essential ions and metabolites. The specific chemical structure of daptomycin includes a complex arrangement of amino acids, contributing to its stability and efficacy. It is typically administered intravenously and is known for its effectiveness against serious infections such as endocarditis and skin infections. Daptomycin is generally well-tolerated, although it may cause side effects such as muscle pain or weakness. Its use is often reserved for cases where other treatments are ineffective, particularly in the context of antibiotic resistance.

CAS 351499-29-1

Daptomycin, 1-[(αS)-2-amino-γ-oxo-α-[(1-oxodecyl)amino]benzenebutanoic acid]-

Daptomycin Impurity 24

Ref: 4Z-PD-122028

Daptomycin Impurity 12

Ref: ST-EA-CP-D73010