CAS 3517-51-9

HYDROCORTISONE 11,17,21-TRIACETATE

Description:

Hydrocortisone 11,17,21-triacetate is a synthetic derivative of hydrocortisone, a corticosteroid hormone that plays a crucial role in various physiological processes, including inflammation and immune response regulation. This compound is characterized by the presence of three acetyl groups attached to the hydroxyl groups at positions 11, 17, and 21 of the hydrocortisone molecule, which enhances its lipophilicity and alters its pharmacokinetic properties. As a glucocorticoid, it exhibits anti-inflammatory and immunosuppressive effects, making it useful in treating conditions such as allergies, asthma, and autoimmune disorders. The compound is typically administered via injection or topical application, depending on the therapeutic need. Its chemical structure contributes to its stability and potency, allowing for effective management of various inflammatory conditions. Additionally, hydrocortisone 11,17,21-triacetate is subject to specific regulations due to its potential for misuse and side effects associated with corticosteroid use, such as adrenal suppression and metabolic changes.

Formula: C₂₇H₃₆O₈

Synonyms:

• 11β,17α,21-Tris(acetyloxy)pregn-4-ene-3,20-dione
• Hydrocortisone 11,17,21-Triacetate
• Pregn-4-ene-3,20-dione, 11,17,21-tris(acetyloxy)-, (11β)-

Hydrocortisone 11,17,21-Triacetate

Controlled Product

CAS: 3517-51-9

Color and Shape: Neat

Ref: 86-MM0187.06

Hydrocortisone 11,17,21-Triacetate

CAS: 3517-51-9

Formula: C₂₇H₃₆O₈

Molecular weight: 488.58

Ref: 4Z-H-103041

11b,17a,21-Tris(acetyloxy)pregn-4-ene-3,20-dione

Controlled Product

CAS: 3517-51-9

Applications 11β,17α,21-Tris(acetyloxy)pregn-4-ene-3,20-dione is an intermediate of Progesterone (P755900), a steroid hormone produced by the corpus luteum. Induces maturation and secretory activity of the uterine endothelium.
References Beyler, R.E., et al.: J. Am. Chem. Soc., 79, 5297 (1957);

Formula: C₂₇H₃₆O₈

Color and Shape: Neat

Molecular weight: 488.57

Ref: TR-T875020