CAS 35179-98-7

Chloromethyl ethyl carbonate

Description:

Chloromethyl ethyl carbonate, with the CAS number 35179-98-7, is an organic compound characterized by its ester functional group. It typically appears as a colorless to pale yellow liquid with a distinctive odor. This compound is known for its reactivity, particularly due to the presence of both a chloromethyl group and an ethyl carbonate moiety, which can participate in various chemical reactions, including nucleophilic substitutions. Chloromethyl ethyl carbonate is soluble in organic solvents, making it useful in organic synthesis and as an intermediate in the production of pharmaceuticals and agrochemicals. Its chemical structure allows it to act as a versatile building block in the synthesis of more complex molecules. However, it is important to handle this compound with care, as it may pose health risks, including irritation to the skin and respiratory system. Proper safety measures, including the use of personal protective equipment and adequate ventilation, are essential when working with this substance in a laboratory or industrial setting.

Formula: C₄H₇ClO₃

InChI: InChI=1/C4H7ClO3/c1-2-7-4(6)8-3-5/h2-3H2,1H3

InChI key: InChIKey=RTFGZMKXMSDULM-UHFFFAOYSA-N

SMILES: C(OCC)(OCCl)=O

Synonyms:

• Carbonic Acid, Chloromethyl Ethyl Ester
• Carbonic acid chloromethyl ester ethyl ester
• Chloromethyl ethyl carbonate
• CHLOROMETHYL CYCLOHEXYL CARBONATE
• Tenofovir Impurity 44
• JMC-3
• CHLOROMETHYL ETHYL CARBONATE (JMC-3)
• Chloromethyl Cyclohexyl Carbonate (JMC-2)

Chloromethyl ethyl carbonate

CAS: 35179-98-7

Formula: C₄H₇ClO₃

Purity: 97%

Color and Shape: Liquid

Molecular weight: 138.5496

Ref: IN-DA0038SP

Chloromethyl ethyl carbonate

CAS: 35179-98-7

Chloromethyl ethyl carbonate

Purity: 97%

Molecular weight: 138.55g/mol

Ref: 54-OR927715

Tenofovir Impurity 53

CAS: 35179-98-7

Formula: C₄H₇ClO₃

Molecular weight: 138.55

Ref: 4Z-T-0297

Chloromethyl ethyl carbonate

CAS: 35179-98-7

Formula: C₄H₇ClO₃

Purity: 97%

Color and Shape: Liquid

Molecular weight: 138.55

Ref: 10-F318221

Chloromethyl Ethyl Carbonate

Controlled Product

CAS: 35179-98-7

Applications A reagent used in the preparation of hepatitis C virus NS3 protease inhibitors and PMPA prodrugs with antiretroviral activity.
References Sheng, X. et al.: Bioorg, Med. Chem. Lett., 169, 3453 (2009); Arimilli, M.N. et al.: Antiviral Chem. Chemother., 8, 557 (1997);

Formula: C₄H₇ClO₃

Color and Shape: Colourless Oily

Molecular weight: 138.55

Ref: TR-C369300

Chloromethyl ethyl carbonate

CAS: 35179-98-7

Chloromethyl ethyl carbonate is an oral prodrug for the treatment of HIV-1 and other viral diseases. It is a compound that is chemically stable and can be recharged with a chemical reaction. Chloromethyl ethyl carbonate inhibits human immunodeficiency virus type 1 (HIV-1) replication in the proximal tubule cells of the kidney. The uptake of chloromethyl ethyl carbonate by proximal tubular cells is dependent on the presence of active substances, such as tenofovir, which can be found in some antiretroviral therapy drugs. This drug has also been shown to have antihypertensive properties in humans.

Formula: C₄H₇ClO₃

Purity: Min. 95%

Color and Shape: Colorless Powder

Molecular weight: 138.55 g/mol

Ref: 3D-FC20250

Tenofovir Impurity 53

CAS: 35179-98-7

Formula: C₄H₇ClO₃

Molecular weight: 138.55

Ref: ST-EA-CP-T5104