CAS 3518-65-8

1-Chloromethanesulfonyl chloride

Description:

1-Chloromethanesulfonyl chloride, with the CAS number 3518-65-8, is an organosulfur compound characterized by the presence of a chloromethyl group and a sulfonyl chloride functional group. It appears as a colorless to pale yellow liquid and is known for its strong reactivity, particularly as a sulfonating agent. This compound is highly polar due to the sulfonyl group, which enhances its solubility in polar solvents. It is sensitive to moisture and can hydrolyze in the presence of water, releasing hydrochloric acid and forming methanesulfonic acid. 1-Chloromethanesulfonyl chloride is primarily used in organic synthesis, particularly for the introduction of sulfonyl groups into various organic molecules, making it valuable in the production of pharmaceuticals and agrochemicals. Due to its reactivity, it must be handled with care, as it can cause severe irritation to the skin, eyes, and respiratory system. Proper safety precautions, including the use of personal protective equipment, are essential when working with this compound.

Formula: CH₂Cl₂O₂S

InChI: InChI=1S/CH2Cl2O2S/c2-1-6(3,4)5/h1H2

InChI key: InChIKey=KQDDQXNVESLJNO-UHFFFAOYSA-N

SMILES: S(CCl)(Cl)(=O)=O

Synonyms:

• (Chloromethyl)sulfonyl chloride
• 1-Chloromethanesulfonyl chloride
• Chloromethanesulfonyl chloride
• Methanesulfonyl chloride, 1-chloro-
• Methanesulfonyl chloride, chloro-

Chloromethylsulfonyl Chloride

CAS: 3518-65-8

Formula: CH₂Cl₂O₂S

Purity: >80.0%(GC)

Color and Shape: Light yellow to Yellow to Orange clear liquid

Molecular weight: 148.99

Ref: 3B-C0924

Chloromethanesulfonyl chloride

CAS: 3518-65-8

Formula: CH₂Cl₂O₂S

Purity: 80%

Color and Shape: Liquid

Molecular weight: 148.9964

Ref: IN-DA003OTZ

Chloromethanesulfonyl chloride

CAS: 3518-65-8

Formula: ClCH₂SO₂Cl

Molecular weight: 149.00

Ref: 7W-GX5399

Chloromethanesulphonyl chloride

CAS: 3518-65-8

Chloromethanesulphonyl chloride

Formula: CH₂Cl₂O₂S

Purity: 95%

Color and Shape: clear. light yellow liquid

Molecular weight: 149.00g/mol

Ref: 54-OR5975

Chloromethylsulphonyl chloride

CAS: 3518-65-8

Formula: CH₂Cl₂O₂S

Purity: 95.0%

Color and Shape: Liquid, Clear

Molecular weight: 148.99

Ref: 10-F120500

Chloromethanesulfonyl Chloride

Controlled Product

CAS: 3518-65-8

Applications Chloromethanesulfonyl Chloride is a very useful intermediate for organic synthesis. It enhances citric acid production by Aspergillus niger NCIM-1696 and increases the yield of citric acid. It also functions as a useful intermediate for pharmaceutical synthesis.
References Mahato, J., et al.: J. Chemtracks, 16, 245 (2014); Shealy, Y. F., et al.: J. Med. Chem., 26, 1168 (1983); Johnson, J. K., et al.: ACS Med. Chem. Lett., 7, 785 (2016)

Formula: CH₂Cl₂O₂S

Color and Shape: Neat

Molecular weight: 149.0

Ref: TR-C427699

Chloromethanesulfonyl chloride, 95%

CAS: 3518-65-8

It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dye stuff. It is synthesis of chloromethanesulfonates and chloromethanesulfonamides. It is also used for conversion of alcohols into the inverted acetates, azides and nitriles, and rearra

Formula: CH₂Cl₂O₂S

Purity: 95%

Color and Shape: Liquid, Clear Colorless to yellow or pale brown

Molecular weight: 148.99

Ref: 02-041486