CAS 35189-28-7

Norgestimate

Description:

Norgestimate is a synthetic progestin, primarily used in hormonal contraceptives. It is a derivative of norethisterone and is characterized by its ability to mimic the natural hormone progesterone. Norgestimate is known for its high oral bioavailability and is often combined with estrogen in contraceptive formulations to prevent ovulation. The substance is typically administered in the form of tablets and is recognized for its relatively low androgenic activity, making it a preferred choice in contraceptive therapies for women who may be sensitive to androgenic side effects. Chemically, norgestimate features a cyclopropane ring, which contributes to its unique pharmacological properties. It is metabolized in the liver to its active form, norgestrel, which exerts the desired contraceptive effects. As with any hormonal medication, norgestimate may have side effects, and its use should be monitored by healthcare professionals to ensure safety and efficacy.

Formula: C₂₃H₃₁NO₃

InChI: InChI=1S/C23H31NO3/c1-4-22-12-10-19-18-9-7-17(24-26)14-16(18)6-8-20(19)21(22)11-13-23(22,5-2)27-15(3)25/h2,14,18-21,26H,4,6-13H2,1,3H3/t18-,19+,20+,21-,22-,23-/m0/s1

InChI key: InChIKey=KIQQMECNKUGGKA-GOMYTPFNSA-N

SMILES: C(C)[C@@]12[C@](OC(C)=O)(C#C)CC[C@]1([C@]3([C@](CC2)([C@@]4(C(CC3)=CC(=NO)CC4)[H])[H])[H])[H]

Synonyms:

• D 138
• Dexnorgestrel acetime
• Norgestimate
• Orf 10131
• Rwj 10131
• d-(17α)-17-Acetoxy-13-ethyl-18,19-dinorpregn-4-en-20-yn-3-one oxime
• 18,19-Dinorpregn-4-en-20-yn-3-one, 17-(acetyloxy)-13-ethyl-, 3-oxime, (17α)-

NORGESTIMATE FOR SYSTEM SUITABILITY CRS

CAS: 35189-28-7

NORGESTIMATE FOR SYSTEM SUITABILITY CRS

Formula: C₂₃H₃₁NO₃

Molecular weight: 369.4971

Ref: 41-Y0000725

NORGESTIMATE CRS

CAS: 35189-28-7

NORGESTIMATE CRS

Formula: C₂₃H₃₁NO₃

Color and Shape: White. Powder.

Molecular weight: 369.4971

Ref: 41-Y0000724

Norgestimate

CAS: 35189-28-7

Estrogens and progestins

Formula: C₂₃H₃₁NO₃

Color and Shape: White Pale Yellow Powder

Molecular weight: 369.23039

Ref: 45-1471914

Norgestimate

CAS: 35189-28-7

Formula: C₂₃H₃₁NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 369.4971

Ref: IN-DA00JNSM

Norgestimate (Mixture of Z and E Isomers)

CAS: 35189-28-7

Formula: C₂₃H₃₁NO₃

Color and Shape: Off-White Solid

Molecular weight: 369.51

Ref: 4Z-N-125

Norgestimate

CAS: 35189-28-7

Norgestimate

Purity: ≥98%

Molecular weight: 369.5g/mol

Ref: 54-BUP02341

Norgestimate

CAS: 35189-28-7

Formula: C₂₃H₃₁NO₃

Purity: (HPLC) ≥ 99.0% (anhydrous)

Color and Shape: White to off-white powder

Molecular weight: 369.50

Ref: 7W-GX3653

Norgestimate

CAS: 35189-28-7

Color and Shape: Neat

Ref: 86-MM0978.00

Norgestimate

Controlled Product

CAS: 35189-28-7

Formula: C₂₃H₃₁NO₃

Color and Shape: Neat

Molecular weight: 369.50

Ref: 04-C15651450

Norgestimate

CAS: 35189-28-7

Norgestimate is an acetylated progestinused in combination with ethinyl estradiol as an oral contraceptive.

Formula: C₂₃H₃₁NO₃

Purity: 96.93%

Color and Shape: White Crystalline Solid

Molecular weight: 369.5

Ref: TM-T7537

Norgestimate

Controlled Product

CAS: 35189-28-7

Applications Progestogen. In combination with estrogen as oral contraceptive.
References Hahn, D.W., et al.: Contraception, 16, 541 (1977), Weintraub, H.S., et al.: J. Pharm. Sci., 67, 1406 (1978),

Formula: C₂₃H₃₁NO₃

Color and Shape: White Solid

Molecular weight: 369.50

Ref: TR-N686000

Norgestimate-d3 (major)

Controlled Product

CAS: 35189-28-7

Applications Norgestimate-d3 is the labeled Norgestimate, a progestogen. In combination with estrogen as oral contraceptive.
References Hahn, D.W., et al.: Contraception, 16, 541 (1977); Weintraub, H.S., et al.: J. Pharm. Sci., 67, 1406 (1978)

Formula: C₂₃H₂₆D₅NO₃

Color and Shape: Neat

Molecular weight: 374.53

Ref: TR-N686003

Norgestimate

CAS: 35189-28-7

Formula: C₂₃H₃₁NO₃

Molecular weight: 369.51

Ref: ST-EA-CP-N55000