CAS 352000-07-8

4H-1-Benzopyran-4-one, 5,6,7-trihydroxy-2-phenyl-, hydrate (1:1)

Description:

4H-1-Benzopyran-4-one, 5,6,7-trihydroxy-2-phenyl-, hydrate (1:1), commonly referred to as a flavonoid compound, exhibits several notable characteristics. This substance features a benzopyran core structure, which is typical of flavonoids, and is characterized by the presence of three hydroxyl groups at positions 5, 6, and 7, contributing to its potential antioxidant properties. The phenyl group at position 2 enhances its aromatic characteristics and may influence its biological activity. As a hydrate, it contains water molecules in its crystalline structure, which can affect its solubility and stability. This compound is often studied for its potential health benefits, including anti-inflammatory and anticancer properties, attributed to its ability to scavenge free radicals and modulate various biochemical pathways. Its applications may extend to food, pharmaceuticals, and cosmetics, where its antioxidant properties can be beneficial. Overall, this compound represents a significant interest in both natural product chemistry and medicinal research.

Formula: C₁₅H₁₀O₅·H₂O

InChI: InChI=1S/C15H10O5.H2O/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12;/h1-7,17-19H;1H2

InChI key: InChIKey=NPXBMGZSFXMEQA-UHFFFAOYSA-N

SMILES: O=C1C=2C(OC(=C1)C3=CC=CC=C3)=CC(O)=C(O)C2O.O

Synonyms:

• 4H-1-Benzopyran-4-one, 5,6,7-trihydroxy-2-phenyl-, monohydrate
• 4H-1-Benzopyran-4-one, 5,6,7-trihydroxy-2-phenyl-, hydrate (1:1)

Baicalein monohydrate

CAS: 352000-07-8

Baicalein monohydrate blocks 12-lipoxygenase, curbs leukotrienes, lysosomal enzymes, Ca2+ dynamics, and fights arthritis.

Formula: C₁₅H₁₂O₆

Color and Shape: Solid

Molecular weight: 288.25

Ref: TM-T69385

Baicalein Monohydrate

Controlled Product

CAS: 352000-07-8

Applications An inhibitor of 12-lipoxygenase, leukotriene biosynthesis and release of lysosomal enzymes. It also inhibits cellular Ca2+ uptake and mobilization and adjuvant-induced arthritis. Baicalein is the flavonoid component of Nepalese and Sino-Japanese crude drugs.
References Nadler, J.L., et al.: J. Clin. Invest., 80, 1763 (1987), Ono, K., et al.: Biochem. Biophys. Res. Commun., 160, 982 (1989), Abe, K., et al.: Chem. Pharm. Bull., 38, 209 (1990)

Formula: C₁₅H₁₂O₆

Color and Shape: Neat

Molecular weight: 288.26

Ref: TR-B115250