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CAS 35211-10-0

:

(±)-Norketamine

Description:
(±)-Norketamine, with the CAS number 35211-10-0, is a chemical compound that serves as a metabolite of ketamine, a well-known anesthetic and analgesic agent. It is classified as a chiral compound, meaning it exists in two enantiomeric forms, which can exhibit different biological activities. Norketamine is primarily recognized for its potential antidepressant effects and its role in modulating synaptic plasticity. The substance has a relatively low molecular weight and is soluble in various organic solvents, which facilitates its use in pharmacological studies. Its mechanism of action is thought to involve antagonism of the N-methyl-D-aspartate (NMDA) receptor, along with interactions with other neurotransmitter systems, including serotonin and dopamine pathways. Due to its psychoactive properties, (±)-Norketamine is of interest in both clinical and research settings, particularly in the context of treatment-resistant depression and other mood disorders. However, its safety profile and long-term effects require further investigation to fully understand its therapeutic potential.
Formula:C12H14ClNO
InChI:InChI=1S/C12H14ClNO/c13-10-6-2-1-5-9(10)12(14)8-4-3-7-11(12)15/h1-2,5-6H,3-4,7-8,14H2
InChI key:InChIKey=BEQZHFIKTBVCAU-UHFFFAOYSA-N
SMILES:NC1(C2=C(Cl)C=CC=C2)C(=O)CCCC1
Synonyms:
  • (±)-Norketamine
  • 2-(o-Chlorophenyl)-2-aminocyclohexanone
  • 2-Amino-2-(2-chlorophenyl)cyclohexan-1-one
  • 2-Amino-2-(o-chlorophenyl)cyclohexanone
  • Cyclohexanone, 2-Amino-2-(2-Chlorophenyl)-
  • N-Demethylketamine
  • 2-Amino-2-(2-chlorophenyl)cyclohexanone
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Found 3 products.
  • Norketamine
    TRC
    + Info

    Norketamine

    Controlled Product
    CAS:
    <p>Applications Norketamine is a metabolite of Ketamine (K165300).<br>References Domino, E., et al.: Anesth. Analg., 61, 87 (1982); Sullivan, H., et al.: J. Med. Chem., 16, 909 (1973); Moreton, J., et al.: J. Pharmacol. Exp. Ther., 203, 303 (1977); Lin, H., et al.: J. Food Drug Anal., 13, 107 (2005);<br></p>
    Formula:C12H14ClNO
    Color and Shape:Neat
    Molecular weight:223.7

    Ref: TR-N692050

    10mg
    155.00€
    100mg
    1,201.00€
    250mg
    2,178.00€
  • Norketamine (1 mg/ml in Acetonitrile)
    TRC
    + Info

    Norketamine (1 mg/ml in Acetonitrile)

    Controlled Product
    CAS:
    Formula:C12H14ClNO
    Color and Shape:Colourless
    Molecular weight:223.7

    Ref: TR-KIT6640

    10x1ml
    597.00€
  • 2-Amino-2-(2-chlorophenyl)cyclohexan-1-one
    Biosynth
    + Info

    2-Amino-2-(2-chlorophenyl)cyclohexan-1-one

    Controlled Product
    CAS:
    <p>2-Amino-2-(2-chlorophenyl)cyclohexan-1-one is an anesthetic drug that belongs to the group of ketamine. It is a chiral compound and has been shown to have central nervous system depressant effects, which are more pronounced than those of ketamine. This drug also affects the cardiovascular system and can cause respiratory depression. 2-Amino-2-(2-chlorophenyl)cyclohexan-1-one has been shown to be metabolized in humans by cytochrome P450 (CYP3A4). It may potentiate the effect of drugs that induce CYP3A4 activity such as erythromycin, rifampin, and phenobarbital.<br> 2-Amino-2-(2-chlorophenyl)cyclohexan-1-one is not active against MRSA or methicillin resistant pseudomonas aeruginosa (MR</p>
    Formula:C12H14ClNO
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:223.7 g/mol

    Ref: 3D-FA164874

    5g
    5,280.00€