CAS 352290-60-9

2,4(1H,3H)-Pyrimidinedione,3-[(2R)-2-amino-2-phenylethyl]-1-[(2,6-difluorophenyl)methyl]-5-(2-fluoro-3-methoxyphenyl)-6-methyl-

Description:

2,4(1H,3H)-Pyrimidinedione, 3-[(2R)-2-amino-2-phenylethyl]-1-[(2,6-difluorophenyl)methyl]-5-(2-fluoro-3-methoxyphenyl)-6-methyl- is a complex organic compound characterized by its pyrimidinedione core structure, which features a bicyclic ring system containing nitrogen atoms. This compound exhibits multiple functional groups, including amine, fluorine, and methoxy substituents, which contribute to its potential biological activity and chemical reactivity. The presence of the amino group suggests possible interactions with biological targets, making it of interest in medicinal chemistry. The difluorophenyl and methoxyphenyl groups enhance its lipophilicity and may influence its pharmacokinetic properties. Additionally, the stereochemistry indicated by the (2R) configuration suggests specific spatial arrangements that could affect the compound's interactions with enzymes or receptors. Overall, this compound's unique structural features may provide insights into its potential applications in drug development or other chemical research areas.

Formula: C₂₇H₂₄F₃N₃O₃

NBI-42902

CAS: 352290-60-9

Formula: C₂₇H₂₄F₃N₃O₃

Molecular weight: 495.50

Ref: 4Z-N-143001

NBI 42902

CAS: 352290-60-9

NBI 42902 is a drug that has been shown to inhibit the uptake of aliphatic hydrocarbons. This inhibition may be due to its ability to act as a potent antagonist of the β-receptor and/or the hydroxy derivative. NBI 42902 was found to have antitumor properties in humans, but not in animals. The drug also has an effect on endometriosis, which may be due to its inhibition of prostaglandin synthesis. NBI 42902 is orally active and binds to receptors in the body, including those for cancerous cells.

Formula: C₂₇H₂₄F₃N₃O₃

Purity: Min. 95%

Molecular weight: 495.49 g/mol

Ref: 3D-FN103814

NBI-42902

CAS: 352290-60-9

NBI-42902 is a potent GnRH receptor antagonist (Ki=0.56 nm, Kd=0.19 nm), suppressing serum LH in macaques without causing histamine release.

Formula: C₂₇H₂₄F₃N₃O₃

Color and Shape: Solid

Molecular weight: 495.49

Ref: TM-T69383