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CAS 352351-61-2

:

Fmoc-2,4-Dichloro-D-phenylalanine

Description:
Fmoc-2,4-Dichloro-D-phenylalanine is a synthetic amino acid derivative commonly used in peptide synthesis and research. It features a 9-fluorenylmethoxycarbonyl (Fmoc) protecting group, which is widely utilized in solid-phase peptide synthesis due to its stability under basic conditions and ease of removal under mild acidic conditions. The presence of two chlorine atoms at the 2 and 4 positions of the phenyl ring enhances its hydrophobic characteristics and can influence the biological activity of peptides incorporating this residue. As a D-amino acid, it exhibits unique stereochemical properties, which can be advantageous in the design of peptides with specific conformational or functional attributes. This compound is typically used in the development of peptide-based drugs and in studies related to protein folding and function. Its CAS number, 352351-61-2, allows for precise identification in chemical databases and literature. Overall, Fmoc-2,4-Dichloro-D-phenylalanine is a valuable tool in the field of medicinal chemistry and peptide research.
Formula:C24H19Cl2NO4
InChI:InChI=1/C24H19Cl2NO4/c25-15-10-9-14(21(26)12-15)11-22(23(28)29)27-24(30)31-13-20-18-7-3-1-5-16(18)17-6-2-4-8-19(17)20/h1-10,12,20,22H,11,13H2,(H,27,30)(H,28,29)/t22-/m1/s1
SMILES:c1ccc2c(c1)c1ccccc1C2COC(=N[C@H](Cc1ccc(cc1Cl)Cl)C(=O)O)O
Synonyms:
  • (2R)-3-(2,4-Dichlorophenyl)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}propanoic acid
  • 2,4-Dichloro-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-phenylalanine
  • D-phenylalanine, 2,4-dichloro-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
  • Fmoc-D-2,4-Dichlorophenylalanine
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