CAS 352431-33-5

Pregna-1,4-diene-3,20-dione,9-fluoro-11,21-dihydroxy-16,17-[[1-(methyl-d3)ethylidene-2,2,2-d3]bis(oxy)]-,(11b,16a)- (9CI)

Description:

Pregna-1,4-diene-3,20-dione, 9-fluoro-11,21-dihydroxy-16,17-[[1-(methyl-d3)ethylidene-2,2,2-d3]bis(oxy)]-, (11b,16a)-, commonly referred to by its CAS number 352431-33-5, is a synthetic steroid compound characterized by its complex structure, which includes multiple functional groups such as hydroxyl (-OH) and ether linkages. This compound features a fluorine atom, which can influence its biological activity and pharmacokinetics. The presence of the d3 isotopes indicates that it has been labeled for use in research, particularly in studies involving metabolic pathways or pharmacodynamics. Its structural modifications suggest potential applications in medicinal chemistry, particularly in the development of corticosteroids or other hormone-related therapies. The compound's stereochemistry, denoted by the (11b,16a) configuration, is crucial for its interaction with biological targets, influencing its efficacy and safety profile. Overall, this compound exemplifies the intricate design often found in steroid derivatives aimed at enhancing therapeutic effects while minimizing side effects.

Formula: C₂₄H₂₅D₆FO₆

Synonyms:

• Triamcinolone-6-D1 Acetonide-D6

Triamcinolone Acetonide-d6

CAS: 352431-33-5

Purity: 99 atom % D

Molecular weight: 440.54

Ref: 3U-D6203

Triamcinolone Acetonide-d7 (major)

Controlled Product

CAS: 352431-33-5, 76-25-5

Applications Triamcinolone Acetonide-d6 is the labeled analogue of Triamcinolone Acetonide (T767165), a glucocorticoid, antiasthmatic (inhalant); antiallergic (nasal).
References Florey, K., et al.: Anal. Profiles Drug Subs., 1, 397 (1972); Bernstein, I.L., et al.: Chest, 81, 20 (1982)

Formula: C₂₄H₂₄D₇FO₆

Color and Shape: Off-White To Beige

Molecular weight: 441.54088

Ref: TR-T767168

Triamcinolone acetonide-d6

CAS: 352431-33-5

Triamcinolone acetonide-d6 is a deuterated compound of Triamcinolone acetonide. Triamcinolone acetonide has a CAS number of 76-25-5. Triamcinolone acetonide is a Corticosteroid. The mechanism of action of triamcinolone acetonide is as a Corticosteroid Hormone Receptor Agonist. It is an anti-inflammatory glucocorticoid used topically in the treatment of various skin disorders. Intralesional, intramuscular, and intra-articular injections are also administered under certain conditions.

Formula: C₂₄H₂₅D₆FO₆

Molecular weight: 440.53

Ref: TM-TMID-0248

TRIAMCINOLONE-6-D1 ACETONIDE-D6

CAS: 352431-33-5

Formula: C₂₄H₃₁FO₆

Color and Shape: Solid

Molecular weight: 440.541g/mol

Ref: IN-DA00C5L5