CAS 352525-91-8

{(E)-2-[4-(trifluoromethyl)phenyl]ethenyl}boronic acid

Description:

{(E)-2-[4-(trifluoromethyl)phenyl]ethenyl}boronic acid, with the CAS number 352525-91-8, is an organoboron compound characterized by the presence of a boronic acid functional group and a vinyl group attached to a phenyl ring that carries a trifluoromethyl substituent. This compound typically exhibits properties such as high reactivity due to the boronic acid moiety, which can participate in various chemical reactions, including Suzuki coupling, a key reaction in organic synthesis for forming carbon-carbon bonds. The trifluoromethyl group enhances the compound's lipophilicity and can influence its electronic properties, making it useful in medicinal chemistry and material science. The E configuration indicates the specific geometric arrangement around the double bond, which can affect the compound's reactivity and interactions. Additionally, boronic acids are known for their ability to form reversible complexes with diols, which is significant in biological applications and sensor development. Overall, this compound's unique structure and functional groups make it valuable in synthetic organic chemistry and related fields.

Formula: C₉H₈BF₃O₂

InChI: InChI=1/C9H8BF3O2/c11-9(12,13)8-3-1-7(2-4-8)5-6-10(14)15/h1-6,14-15H/b6-5+

TRANS-2-(4-(TRIFLUOROMETHYL)PHENYL)-

CAS: 352525-91-8

Formula: C₉H₈BF₃O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 215.9648

Ref: IN-DA00C0YH

trans-2-[4-(Trifluoromethyl)phenyl]vinylboronic acid

CAS: 352525-91-8

trans-2-[4-(Trifluoromethyl)phenyl]vinylboronic acid

Purity: 98%

Color and Shape: White To Off White Solid

Molecular weight: 215.96g/mol

Ref: 54-PC412074

(4-(Trifluoromethyl)styryl)boronic acid

CAS: 352525-91-8

Formula: C₉H₈BF₃O₂

Purity: 98%

Molecular weight: 215.97

Ref: 10-F217424

Aβ aggregation-IN-1

CAS: 352525-91-8

Aβ aggregation-IN-1 (Compound 1b) is an inhibitor of amyloid-beta precursor protein. It suppresses the aggregation and disaggregation of amyloid-beta fibrils with IC50 values of 3.92 and 7.19 M, respectively. Additionally, Aβ aggregation-IN-1 reduces malondialdehyde formation in neuronal cells, increases intracellular levels of reduced glutathione (GSH), and inhibits caspase 3.

Formula: C₉H₈BF₃O₂

Color and Shape: Solid

Molecular weight: 215.965

Ref: TM-T204182