CAS 35303-12-9
:Kinamycin A
Description:
Kinamycin A is a naturally occurring antibiotic belonging to the class of compounds known as ansamycins. It is produced by certain strains of the bacterium Streptomyces. The molecular structure of Kinamycin A features a complex bicyclic core, which is characteristic of ansamycin antibiotics, and it contains a unique side chain that contributes to its biological activity. Kinamycin A exhibits potent antibacterial properties, particularly against Gram-positive bacteria, and has shown efficacy in inhibiting the growth of various cancer cell lines, making it of interest in cancer research. The compound operates through mechanisms that may involve the inhibition of DNA-dependent RNA polymerase, thereby disrupting transcription in susceptible organisms. Kinamycin A is also noted for its potential as a lead compound in the development of new therapeutic agents. Its stability, solubility, and bioavailability are important factors that influence its pharmacological applications. As with many natural products, further studies are ongoing to fully elucidate its mechanisms of action and potential therapeutic uses.
Formula:C24H20N2O10
InChI:InChI=1/C24H20N2O10/c1-8(27)34-22-17-15(21(33)23(35-9(2)28)24(22,4)36-10(3)29)14-16(18(17)26-25)20(32)13-11(19(14)31)6-5-7-12(13)30/h5-7,21-23,33H,1-4H3,(H-,30,31,32)/t21-,22+,23+,24+/m0/s1
InChI key:InChIKey=JIYPIUWXCOFASH-OLKYXYMISA-N
SMILES:O(C(C)=O)[C@@H]1C2=C(C3=C(C2=[N+]=[N-])C(=O)C=4C(C3=O)=CC=CC4O)[C@H](O)[C@@H](OC(C)=O)[C@@]1(OC(C)=O)C
Synonyms:- Kinamycin A
- 1H-Benzo[b]fluorene-5,10-dione, 1,2,3-tris(acetyloxy)-11-diazo-2,3,4,11-tetrahydro-4,9-dihydroxy-2-methyl-, [1R-(1α,2α,3β,4α)]-
- (1R,2R,3R,4S)-1,2,3-Tris(acetyloxy)-11-diazo-2,3,4,11-tetrahydro-4,9-dihydroxy-2-methyl-1H-benzo[b]fluorene-5,10-dione
- Kinamycin
- 1H-Benzo[b]fluorene-5,10-dione, 1,2,3-tris(acetyloxy)-11-diazo-2,3,4,11-tetrahydro-4,9-dihydroxy-2-methyl-, (1R,2R,3R,4S)-
- kinamycin A
- See more synonyms
Sort by
The purity filter is not visible because current products do not have associated purity data for filtering.
Found 1 products.
Kinamycin A
CAS:<p>Kinamycin A possesses antibacterial and antimycobacterial properties, yet it exhibits reduced efficacy against Gram-negative bacteria.</p>Formula:C24H20N2O10Color and Shape:SolidMolecular weight:496.423
