CAS 35337-98-5
:Monocrotaline, N-oxide
Description:
Monocrotaline N-oxide is a chemical compound derived from monocrotaline, which is an alkaloid found in plants of the Crotalaria genus. It is characterized by its molecular structure, which includes a pyrrolidine ring and an N-oxide functional group. This compound is known for its biological activity, particularly its potential toxicity and effects on the cardiovascular system. Monocrotaline N-oxide has been studied for its role in inducing pulmonary hypertension and other pathological conditions in various animal models. Its mechanism of action is thought to involve the formation of reactive metabolites that can cause cellular damage and inflammation. Additionally, it is important to handle this compound with care due to its toxicological properties. In terms of physical properties, monocrotaline N-oxide is typically a solid at room temperature, with specific solubility characteristics that may vary depending on the solvent used. Overall, this compound serves as a significant subject of research in toxicology and pharmacology, particularly concerning its effects on human health and environmental safety.
Formula:C16H23NO7
InChI:InChI=1S/C16H23NO7/c1-9-13(18)24-11-5-7-17(22)6-4-10(12(11)17)8-23-14(19)16(3,21)15(9,2)20/h4,9,11-12,20-21H,5-8H2,1-3H3
InChI key:InChIKey=LHVAZUAALQTANZ-UHFFFAOYSA-N
SMILES:O=N12C3C(CC1)OC(=O)C(C)C(C)(O)C(C)(O)C(=O)OCC3=CC2
Synonyms:- 20-Norcrotalanan-11,15-dione, 14,19-dihydro-12,13-dihydroxy-, 4-oxide, (13α,14α)-
- Monocrotaline oxide
- 2H-[1,6]Dioxacycloundecino[2,3,4-gh]pyrrolizine-2,6(3H)-dione, 4,5,8,10,12,13,13a,13b-octahydro-4,5-dihydroxy-3,4,5-trimethyl-, 11-oxide, (3R,4S,5S,13aR,13bR)-
- Monocrotaline, N-oxide
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Found 12 products.
(13R,14R)-14,19-Dihydro-12,13-dihydroxy-20-norcrotalanan-11,15-dione 4-oxide
CAS:Formula:C16H23NO7Purity:95%Color and Shape:SolidMolecular weight:341.3563Monocrotaline N-Oxide
CAS:Formula:C16H23NO7Color and Shape:White To Off-White SolidMolecular weight:341.36Monocrotaline N-Oxide
CAS:<p>Monocrotaline N-Oxide is a monocrotaline metabolite.</p>Formula:C16H23NO7Purity:98.31%Color and Shape:SolidMolecular weight:341.36Monocrotaline n-oxide
CAS:Natural alkaloidFormula:C16H23NO7Purity:≥ 98.0 % (HPLC)Color and Shape:PowderMolecular weight:341.36Monocrotaline N-Oxide
CAS:<p>Applications Monocrotaline N-oxide is a pyrrolizidine alkaloid that is hepatoxic to livestock and carcinogenic to rats. Monocrotaline N-oxide is extracted from Crotalaria grahamiana, a legume-bearing, perennial shrub that grows in South India, and in some parts of Kenya.<br>References Bünemann, E., et al.: Plant and Soil, 264, 195 (2004); Davenport, J. & Conner, W.: J. Insect Sci., 3, No pp. given (2003); Wang, J., et al.: Asian J. Trad. Med., 4, 41 (2009)<br></p>Formula:C16H23NO7Purity:>80%Color and Shape:NeatMolecular weight:341.36Monocrotaline N-Oxide-D4
CAS:Controlled Product<p>Applications Monocrotaline N-oxide-D4 is a labelled analogue of Monocrotaline N-oxide (M526005). Monocrotaline N-oxide is a pyrrolizidine alkaloid that is hepatoxic to livestock and carcinogenic to rats. Monocrotaline N-oxide is extracted from Crotalaria grahamiana, a legume-bearing, perennial shrub that grows in South India, and in some parts of Kenya.<br>References Bünemann, E., et al.: Plant and Soil, 264, 195 (2004); Davenport, J. & Conner, W.: J. Insect Sci., 3, No pp. given (2003); Wang, J., et al.: Asian J. Trad. Med., 4, 41 (2009)<br></p>Formula:C16D4H19NO7Color and Shape:NeatMolecular weight:345.381Monocrotaline N-oxide
CAS:<p>Monocrotaline N-oxide is a metabolite of monocrotaline. Monocrotaline is an alkaloid that is found in plants and has been used as a rodenticide and insecticide. The LC-MS/MS method was developed for the analysis of monocrotaline N-oxide. The method is selective, sensitive, and accurate. It has been shown to be effective in the detection of retrorsine and retronecine esters in rat liver microsomes. Monocrotaline N-oxide has been shown to have skin cancer promoting effects in rats when applied to skin at doses of 400 ppm or greater. This metabolite also has an effect on uptake by human liver cells, which may be due to its ability to form a matrix with proteins present in the cell membrane.</p>Formula:C16H23NO7Purity:Min. 95%Color and Shape:PowderMolecular weight:341.36 g/mol
