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CAS 3534-50-7

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3,5,6-Trifluoropyridin-2-amine

Description:
3,5,6-Trifluoropyridin-2-amine is an organic compound characterized by its pyridine ring substituted with three fluorine atoms and an amino group. The presence of the trifluoromethyl groups at the 3, 5, and 6 positions significantly influences its chemical properties, enhancing its reactivity and polarity. This compound is typically a colorless to pale yellow liquid or solid, depending on its form and purity. It exhibits moderate solubility in polar solvents due to the electronegative fluorine atoms, which can engage in hydrogen bonding and dipole interactions. The amino group contributes to its basicity and potential for forming various derivatives through nucleophilic substitution reactions. 3,5,6-Trifluoropyridin-2-amine is of interest in medicinal chemistry and agrochemicals, as it can serve as a building block for the synthesis of biologically active compounds. Safety precautions should be observed when handling this substance, as it may pose health risks, including irritation to the skin and respiratory system.
Formula:C5H3F3N2
InChI:InChI=1/C5H3F3N2/c6-2-1-3(7)5(9)10-4(2)8/h1H,(H2,9,10)
SMILES:c1c(c(F)nc(c1F)N)F
Synonyms:
  • 2-Pyridinamine, 3,5,6-Trifluoro-
  • 2-Amino-3,5,6-trifluoropyridine
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