CAS 353483-92-8

Formula: C22H20N2O2S

InChI: InChI=1S/C22H20N2O2S/c23-27(25,26)15-11-12-21-20(13-15)17-8-4-10-19(17)22(24-21)18-9-3-6-14-5-1-2-7-16(14)18/h1-9,11-13,17,19,22,24H,10H2,(H2,23,25,26)

InChI key: SIZWDJIHABLBSP-UHFFFAOYSA-N

SMILES: C1C=CC2C1C(NC3=C2C=C(C=C3)S(=O)(=O)N)C4=CC=CC5=CC=CC=C54

TQS

CAS: 353483-92-8

Formula: C₂₂H₂₀N₂O₂S

Purity: 95%

Color and Shape: Solid

Molecular weight: 376.4714

Ref: IN-DA00CNAW

TQS

CAS: 353483-92-8

TQS

Formula: C₂₂H₂₀N₂O₂S

Purity: ≥98%

Molecular weight: 376.481

Ref: 54-BUP09851

TQS

CAS: 353483-92-8

TQS (4-Naphthalen-1-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide) is a positive allosteric modulator of α7 nACh receptors.

Formula: C₂₂H₂₀N₂O₂S

Purity: 98.56%

Color and Shape: White Solid

Molecular weight: 376.47

Ref: TM-T23469

TQS

CAS: 353483-92-8

4-(Naphthalen-1-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide

Formula: C₂₂H₂₀N₂O₂S

Purity: 99%

Molecular weight: 376.47

Ref: IN-DG01162646

TQS

Controlled Product

CAS: 353483-92-8

Applications TQS is a positive allosteric modulator (Type II) of alpha7 nACh receptors, functional human α7 nicotinic acetylcholine receptor (nAChR) generated from Escherichia coli that opens a new avenue for producing mammalian Cys-loop receptors to facilitate structure-based rational drug design.
References Tillman, T. S., et al.: J. Biol. Chem., 291, 18276 (2016)

Formula: C₂₂H₂₀N₂O₂S

Color and Shape: Neat

Molecular weight: 376.47

Ref: TR-T700565