CAS 35380-71-3

Estradiol hemihydrate

Description:

Estradiol hemihydrate is a synthetic form of the naturally occurring estrogen estradiol, commonly used in hormone replacement therapy and various medical applications. It is characterized by its molecular formula, which includes a hemihydrate form indicating the presence of water molecules associated with the compound. Estradiol hemihydrate typically appears as a white to off-white crystalline powder and is soluble in organic solvents such as ethanol and methanol, but has limited solubility in water. The substance exhibits estrogenic activity, binding to estrogen receptors and influencing various physiological processes, including reproductive functions and bone density regulation. Its pharmacological effects are significant in treating conditions related to estrogen deficiency, such as menopausal symptoms and certain types of hormone-sensitive cancers. Safety and efficacy profiles are well-studied, and it is essential to consider potential side effects and contraindications when prescribing this compound. As with all medications, proper dosage and administration are crucial for achieving therapeutic benefits while minimizing risks.

Formula: C₁₈H₂₄O₂H₂O

InChI: InChI=1S/C18H24O2.H2O/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20;/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3;1H2/t14-,15-,16+,17+,18+;/m1./s1

InChI key: InChIKey=QJNCGXGNKJUDEM-CMZLOHJFSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@](C=4C(CC3)=CC(O)=CC4)(CC1)[H])[H])(CC[C@@H]2O)[H].O

Synonyms:

• (17Beta)-Estra-1,3,5(10)-Triene-3,17-Diol Hydrate (2:1)
• Estra-1,3,5(10)-triene-3,17-diol (17beta)-, hydrate (2:1)
• Estra-1,3,5(10)-triene-3,17-diol (17β)-, hydrate (2:1)
• Estra-1,3,5(10)-triene-3,17beta-diol hydrate (2:1)
• Estrasorb
• Unii-Cxy7B3Q98Z
• beta-Estradiol hemihydrate
• beta-Estradiol semihydrate
• β-Estradiol hemihydrate
• β-Estradiol semihydrate
• Estradiol hemihydrate

ESTRADIOL FOR PEAK IDENTIFICATION CRS

CAS: 35380-71-3

ESTRADIOL FOR PEAK IDENTIFICATION CRS

Ref: 41-Y0000314

Estradiol hemihydrate

CAS: 35380-71-3

Estradiol hemihydrate

Formula: C₁₈H₂₄O₂

Purity: 96.3%

Color and Shape: White

Molecular weight: 272.17763

Ref: 47-729

ESTRADIOL HEMIHYDRATE CRS

CAS: 35380-71-3

ESTRADIOL HEMIHYDRATE CRS

Formula: C₁₈H₂₄O₂

Color and Shape: Crystalline Powder. White. Powder.

Molecular weight: 272.382

Ref: 41-E1620000

Estradiol

CAS: 35380-71-3

Estrogens and progestins

Formula: C₁₈H₂₄O₂H₂O

Color and Shape: White Cream Crystalline Powder Crystals

Molecular weight: 281.39

Ref: 45-1250008

Estradiol Hemihydrate

CAS: 35380-71-3

Formula: C₁₈H₂₄O₂H₂O

Color and Shape: Neat

Molecular weight: 562.78

Ref: 86-MM0300.00

Estradiol hemihydrate

CAS: 35380-71-3

Estradiol hemihydrate: major female hormone, boosts neural differentiation, studied for cancer and neurodegenerative disease.

Formula: C₁₈H₂₆O₃

Color and Shape: Solid

Molecular weight: 281.39

Ref: TM-T72390

Estradiol RS

CAS: 35380-71-3

Color and Shape: Off-White Solid Powder

Ref: 2K-2002000021

Estradiol hemihydrate

Controlled Product

CAS: 35380-71-3

Estradiol hemihydrate is a synthetic estrogen. It binds to estrogen receptors, causing the activation of DNA transcription and synthesis of messenger RNA. Estradiol hemihydrate has been used for the treatment of various symptoms, such as menopause, osteoporosis, breast cancer, and metabolic disorders. The drug is most often administered by injection or in a polymeric matrix that dissolves slowly in the mouth. The recommended dose is between 0.5mg and 1mg per day. Estradiol hemihydrate can be detected in plasma using an analytical method called liquid chromatography-tandem mass spectrometry (LC-MS/MS).

Formula: (C₁₈H₂₄O₂)₂•H₂O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 562.78 g/mol

Ref: 3D-FE31861

Estradiol Hemihydrate

CAS: 35380-71-3

Color and Shape: Neat

Ref: 61-FOR0300.00