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CAS 354-24-5

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2-Chloro-2,2-difluoroacetyl chloride

Description:
2-Chloro-2,2-difluoroacetyl chloride, with the CAS number 354-24-5, is an organofluorine compound characterized by its unique structure, which includes a chloro group and two fluorine atoms attached to the acetyl chloride moiety. This compound is typically a colorless to pale yellow liquid with a pungent odor, indicative of its reactivity and potential hazards. It is known for its role as an acylating agent in organic synthesis, particularly in the introduction of the difluoroacetyl group into various substrates. The presence of both chlorine and fluorine atoms contributes to its electrophilic nature, making it a useful reagent in the synthesis of pharmaceuticals and agrochemicals. However, it is also important to handle this compound with care due to its corrosive properties and potential health hazards, including irritation to the skin, eyes, and respiratory system. Proper safety measures, including the use of personal protective equipment and working in a well-ventilated area or fume hood, are essential when working with this chemical.
Formula:C2Cl2F2O
InChI:InChI=1S/C2Cl2F2O/c3-1(7)2(4,5)6
InChI key:InChIKey=AZPWOLJQERBBBM-UHFFFAOYSA-N
SMILES:C(C(Cl)=O)(Cl)(F)F
Synonyms:
  • 2-Chloro-2,2-difluoroacetyl chloride
  • Acetyl chloride, 2-chloro-2,2-difluoro-
  • Acetyl chloride, chlorodifluoro-
  • Difluorochloroacetyl chloride
  • Chlorodifluoroacetyl chloride
  • Chlorodifluoroacetyl chloride
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