CAS 35409-55-3

N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-γ-glutamyl-L-γ-glutamyl-L-γ-glutamyl-L-γ-glutamyl-L-γ-glutamyl-L-glutamic acid

Description:

The chemical substance known as N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-γ-glutamyl-L-γ-glutamyl-L-γ-glutamyl-L-γ-glutamyl-L-γ-glutamyl-L-glutamic acid, with CAS number 35409-55-3, is a complex peptide derivative. It features a pteridine moiety, which is indicative of its potential biological activity, particularly in relation to folate metabolism and cellular processes. The presence of multiple γ-glutamyl residues suggests that it may have enhanced solubility and stability in physiological conditions. This compound is likely to exhibit properties associated with amino acids and peptides, such as being hydrophilic due to its multiple carboxyl groups, which can participate in hydrogen bonding. Its structure implies potential applications in biochemistry and pharmacology, particularly in drug design or as a biochemical probe. However, specific characteristics such as solubility, melting point, and biological activity would require empirical data for precise evaluation.

Formula: C₄₄H₅₄N₁₂O₂₁

InChI: InChI=1S/C44H54N12O21/c45-44-55-35-34(37(65)56-44)48-21(18-47-35)17-46-20-3-1-19(2-4-20)36(64)54-27(43(76)77)9-15-32(61)52-25(41(72)73)7-13-30(59)50-23(39(68)69)5-11-28(57)49-22(38(66)67)6-12-29(58)51-24(40(70)71)8-14-31(60)53-26(42(74)75)10-16-33(62)63/h1-4,18,22-27,46H,5-17H2,(H,49,57)(H,50,59)(H,51,58)(H,52,61)(H,53,60)(H,54,64)(H,62,63)(H,66,67)(H,68,69)(H,70,71)(H,72,73)(H,74,75)(H,76,77)(H3,45,47,55,56,65)/t22-,23-,24-,25-,26-,27-/m0/s1

InChI key: InChIKey=AIPNSTFJYXXLIP-QCOJBMJGSA-N

SMILES: O=C1C=2C(NC=C(CNC3=CC=C(C(N[C@@H](CCC(N[C@@H](CCC(N[C@@H](CCC(N[C@@H](CCC(N[C@@H](CCC(N[C@@H](CCC(O)=O)C(O)=O)=O)C(O)=O)=O)C(O)=O)=O)C(O)=O)=O)C(O)=O)=O)C(O)=O)=O)C=C3)N2)=NC(N)=N1

Synonyms:

• L-Glutamic acid, N-[4-[[(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-γ-glutamyl-L-γ-glutamyl-L-γ-glutamyl-L-γ-glutamyl-L-γ-glutamyl-
• L-Glutamic acid, N-[N-[N-[N-[N-[N-[4-[[(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-γ-glutamyl]-L-γ-glutamyl]-L-γ-glutamyl]-L-γ-glutamyl]-L-γ-glutamyl]-
• N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-γ-glutamyl-L-γ-glutamyl-L-γ-glutamyl-L-γ-glutamyl-L-γ-glutamyl-L-glutamic acid
• Pteroyl-γ-hexaglutamate
• L-Glutamic acid, N-[4-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-γ-glutamyl-L-γ-glutamyl-L-γ-glutamyl-L-γ-glutamyl-L-γ-glutamyl-

Hexaglutamate folate

CAS: 35409-55-3

Hexaglutamate folate, a natural folic acid form, requires deconjugation for absorption; its deficiency can lead to anemia and numerous chronic diseases.

Formula: C₄₄H₅₄N₁₂O₂₁

Color and Shape: Solid

Molecular weight: 1086.97

Ref: TM-T25496