CAS 3543-75-7: Bendamustine hydrochloride

Description:Bendamustine hydrochloride is a synthetic alkylating agent used primarily in oncology for the treatment of certain types of cancer, including chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphoma. It is classified as a nitrogen mustard derivative and exhibits both alkylating and antimetabolite properties, which contribute to its effectiveness in disrupting DNA synthesis and cell division in rapidly dividing cancer cells. The compound is typically administered intravenously and is known for its relatively favorable side effect profile compared to other chemotherapeutic agents. Bendamustine hydrochloride is soluble in water and exhibits stability under acidic conditions, making it suitable for formulation in injectable solutions. Its mechanism of action involves the formation of DNA cross-links, leading to apoptosis in malignant cells. Additionally, it has been noted for its immunomodulatory effects, which may enhance the immune response against tumors. As with all chemotherapeutic agents, careful monitoring for adverse effects and patient response is essential during treatment.

Formula:C₁₆H₂₁Cl₂N₃O₂·ClH

InChI:InChI=1S/C16H21Cl2N3O2.ClH/c1-20-14-6-5-12(21(9-7-17)10-8-18)11-13(14)19-15(20)3-2-4-16(22)23;/h5-6,11H,2-4,7-10H2,1H3,(H,22,23);1H

InChI key:InChIKey=ZHSKUOZOLHMKEA-UHFFFAOYSA-N

SMILES:Cl.O=C(O)CCCC1=NC=2C=C(C=CC2N1C)N(CCCl)CCCl

Synonyms:
1-Methyl-5-Bis(2-Chloroethyl)Amino-2-Benzimidazolinebutryric Acid Hydrochloride
1-Methyl-5-Bis(2-Chloroethyl)Amino-2-Benzimidazolinebutryricacihydrochlor
1H-Benzimidazole-2-butanoic acid, 5-[bis(2-chloroethyl)amino]-1-methyl-, hydrochloride (1:1)
1H-Benzimidazole-2-butanoic acid, 5-[bis(2-chloroethyl)amino]-1-methyl-, monohydrochloride
2-Benzimidazolebutyric acid, 5-[bis(2-chloroethyl)amino]-1-methyl-, monohydrochloride
4-[5-[Bis(2-Chloroethyl)Amino]-1-Methylbenzimidazol-2-Yl]Butanoic Acid Hydrochloride
4-[5-[Bis(2-chloroethyl)amino]-1-methyl-benzimidazol-2-yl]butyric acid hydrochloride
4-{5-[bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazol-2-yl}butanoic acid hydrochloride (1:1)
Bendamustin HCL
Bendamustin Hydrochloride
See more synonyms
Bendamustine Hcl
Bendit
Cytostasan
CytostasanHCl
Gamma(1-Methyl-5-Bis(Beta-Chloraethyl)Aminobenzimidazoyl-2)Buttersaeurehydro
Imet 3393
Purplz
Ribomustin
Sdx 105
Treanda
Zimet 33/93

Found 14 products.

Product data	Purity	Price range	Estimated delivery
Bendamustine Hydrochloride REF: 45-1065221CAS: 3543-75-7	- - -	509.00 €	Mon 14 Apr 25
Bendamustine hydrochloride REF: TM-T0095CAS: 3543-75-7	97.71%	50.00 €~344.00 €	Tue 15 Apr 25
4-[5-[Bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid hydrochloride REF: IN-DA0039BQCAS: 3543-75-7	99%	51.00 €~552.00 €	Tue 15 Apr 25
Bendamustine hydrochloride REF: 54-OR1012316CAS: 3543-75-7	99%	42.00 €~3,045.00 €	Wed 16 Apr 25
Bendamustine-d4 HCl REF: 4Z-B-436CAS: 3543-75-7	- - -	To inquire	Wed 16 Apr 25
Bendamustine hydrochloride REF: 54-BUP15045CAS: 3543-75-7	98.02%	114.00 €~700.00 €	Wed 16 Apr 25
Bendamustine HCl REF: 4Z-B-435CAS: 3543-75-7	- - -	To inquire	Wed 16 Apr 25
Bendamustine Hydrochloride REF: 86-MM0154.00CAS: 3543-75-7	- - -	995.00 €	Mon 21 Apr 25
Bendamustine hydrochloride REF: 7W-GP6515CAS: 3543-75-7	≥ 99.0%	156.00 €~389.00 €	Tue 22 Apr 25
Bendamustine Hydrochloride REF: TR-B132500CAS: 3543-75-7	- - -	151.00 €~422.00 €	Fri 25 Apr 25
Bendamustine-d6 (major) Hydrochloride REF: TR-B132502CAS: 3543-75-7	- - -	312.00 €~2,024.00 €	Fri 25 Apr 25
4-(5-(Bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid hydrochloride REF: 10-F223196CAS: 3543-75-7	95.0%	To inquire	Fri 25 Apr 25
Bendamustine HCl - Bio-X ™ REF: 3D-BB164239CAS: 3543-75-7	Min. 95%	147.00 €	Mon 28 Apr 25
Bendamustine hydrochloride REF: 3D-FB18163CAS: 3543-75-7	Min. 98 Area-%	245.00 €~1,376.00 €	Mon 28 Apr 25