CAS 3544-24-9

3-Aminobenzamide

Description:

3-Aminobenzamide, with the CAS number 3544-24-9, is an organic compound characterized by the presence of an amino group (-NH2) and a benzamide functional group. It features a benzene ring substituted with an amino group at the meta position relative to the amide group. This compound is typically a white to off-white crystalline solid, and it is soluble in polar solvents such as water and alcohols, owing to the presence of the amino and amide functionalities that can engage in hydrogen bonding. 3-Aminobenzamide is often used in biochemical research, particularly in studies involving enzyme inhibition and as a precursor in the synthesis of various pharmaceuticals. Its reactivity is influenced by the electron-donating nature of the amino group, which can participate in nucleophilic reactions. Additionally, it may exhibit biological activity, making it of interest in medicinal chemistry. Safety data should be consulted for handling, as with any chemical substance, to ensure proper precautions are taken.

Formula: C₇H₈N₂O

InChI: InChI=1S/C7H8N2O/c8-6-3-1-2-5(4-6)7(9)10/h1-4H,8H2,(H2,9,10)

InChI key: InChIKey=GSCPDZHWVNUUFI-UHFFFAOYSA-N

SMILES: C(N)(=O)C1=CC(N)=CC=C1

Synonyms:

• 3-(Aminocarbonyl)aniline
• 3-Aminobenzamide
• 3-Carbamoylaniline
• 3-Carboxamidoaniline
• 3544-24-9
• Benzamide, 3-amino-
• Benzamide, m-amino-
• Ino 1001
• NSC 36962
• Sr 4294
• Wd 97-000835
• [3-(Aminocarbonyl)phenyl]amine
• m-Aminobenzamide
• 3-AB, 3-ABA
• 3-AB
• 3-ABA
• m-Amino Benzamide 3-Amino Benzamide
• 3-Aminobenzamide,98%
• 3-amino-benzamid
• m-amino-benzamid
• Benzamide, 3-amino-(9CI)

3-Aminobenzamide, 98%

CAS: 3544-24-9

3-Aminobenzamide is used as an endogenous poly-ADP-ribosyltransferase inhibitor. Through its effects on PARPs, 3-amino benzamide causes telomere shortening and stimulates angiogenesis. It displays neuroprotective, anti-necrotic effects. This Thermo Scientific Chemicals brand product was originally p

Formula: C₇H₈N₂O

Purity: 98%

Color and Shape: Pale cream to cream to pale brown, Powder

Molecular weight: 136.15

Ref: 02-A10793

3-Aminobenzamide

CAS: 3544-24-9

Formula: C₇H₈N₂O

Purity: 97%

Color and Shape: Solid

Molecular weight: 136.1512

Ref: IN-DA0037C4

3-Aminobenzamide

CAS: 3544-24-9

3-Aminobenzamide

Purity: 98%

Color and Shape: Off-White Powder

Molecular weight: 136.15g/mol

Ref: 54-BIA0116

3-Aminobenzamide

CAS: 3544-24-9

3-Aminobenzamide

Purity: ≥98%

Molecular weight: 136.15g/mol

Ref: 54-BUP17074

3-Aminobenzamide

CAS: 3544-24-9

3-Aminobenzamide

Formula: C₇H₈N₂O

Purity: 98%

Color and Shape: cream powder

Molecular weight: 136.15g/mol

Ref: 54-OR1322

3-Aminobenzamide

CAS: 3544-24-9

Formula: C₇H₈N₂O

Molecular weight: 136.15

Ref: 7W-GK4398

3-Aminobenzamide

CAS: 3544-24-9

Formula: C₇H₈N₂O

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 136.15

Ref: 3B-A0630

3-Aminobenzamide

CAS: 3544-24-9

3-Aminobenzamide (PARP-IN-1) is an effective inhibitor of PARP (IC50<50 nM in CHO cells) and a mediator of oxidant-induced myocyte dysfunction during

Formula: C₇H₈N₂O

Purity: 98.4% - 99.5%

Color and Shape: White To Off-White Powder

Molecular weight: 136.15

Ref: TM-T6329

3-Aminobenzamide

CAS: 3544-24-9

Formula: C₇H₈N₂O

Molecular weight: 136.15

Ref: ST-EA-CP-CS0550

3-Aminobenzamide

CAS: 3544-24-9

3-Aminobenzamide is a drug that has been shown to be effective in the treatment of temozolomide-induced neuronal death. 3-Aminobenzamide inhibits the synthesis of ATP and blocks its binding to the atp-binding cassette transporter, which prevents the transport of this nucleotide into cells. This results in cell death due to insufficient energy metabolism and inability to repair DNA damage. 3-Aminobenzamide also increases production of reactive oxygen species, which are involved in reperfusion injury and myocardial infarcts. 3-Aminobenzamide is used as a model system for studying DNA repair and energy metabolism.

Formula: C₇H₈N₂O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 136.15 g/mol

Ref: 3D-FA71335

3-Aminobenzamide

CAS: 3544-24-9

Formula: C₇H₈N₂O

Purity: 97%

Color and Shape: Solid

Molecular weight: 136.154

Ref: 10-F018167

3-Aminobenzamide

Controlled Product

CAS: 3544-24-9

Applications 3-Aminobenzamide is used in biological studies for the inhibition of matrix metalloproteinase-2 by PARP inhibitors.
References Nicolescu, A.C., et al.: Biochem. Biophys. Res. Commun., 387, 646 (2009); Purnell, M.R., et al.: Biochem. J., 185, 775 (1980); Morgan, W.F., et al.: Cancer Res., 43, 3104 (1983)

Formula: C₇H₈N₂O

Color and Shape: Neat

Molecular weight: 136.15

Ref: TR-A587150