CAS 3544-94-3

Chloramphenicol succinate

Description:

Chloramphenicol succinate is a derivative of chloramphenicol, an antibiotic that is effective against a wide range of bacteria. This compound is characterized by its esterification with succinic acid, which enhances its solubility and stability compared to its parent compound. Chloramphenicol succinate is typically a white to off-white crystalline powder, and it is soluble in water, making it suitable for various pharmaceutical formulations. The compound retains the antibacterial properties of chloramphenicol, which works by inhibiting bacterial protein synthesis. It is primarily used in the treatment of serious infections caused by susceptible organisms, particularly in cases where other antibiotics may not be effective. Due to its potential side effects, including bone marrow suppression, its use is often limited to specific clinical situations. Additionally, chloramphenicol succinate is subject to regulatory scrutiny, and its use is monitored to prevent adverse reactions. Overall, this compound exemplifies the modifications made to enhance the pharmacological properties of existing antibiotics.

Formula: C₁₅H₁₆Cl₂N₂O₈

InChI: InChI=1S/C15H16Cl2N2O8/c16-14(17)15(24)18-10(7-27-12(22)6-5-11(20)21)13(23)8-1-3-9(4-2-8)19(25)26/h1-4,10,13-14,23H,5-7H2,(H,18,24)(H,20,21)/t10-,13-/m1/s1

InChI key: InChIKey=LIRCDOVJWUGTMW-ZWNOBZJWSA-N

SMILES: [C@@H]([C@H](O)C1=CC=C(N(=O)=O)C=C1)(NC(C(Cl)Cl)=O)COC(CCC(O)=O)=O

Synonyms:

• (2-((Dichloroacetyl)amino)-3-hydroxy-3-(4-nitrophenyl)propyl) hydrogen (R-(R*,R*))-succinate
• 4-{2-[(Dichloroacetyl)Amino]-3-Hydroxy-3-(4-Nitrophenyl)Propoxy}-4-Oxobutanoic Acid
• 4-{[(2R,3R)-2-[(dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl]oxy}-4-oxobutanoic acid
• Acetamide, 2,2-dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-nitrophenethyl]-, α-(hydrogen succinate), <span class="text-smallcaps">D</span>-(-)-threo-
• Brn 3228488
• Butanedioic acid, mono[(2R,3R)-2-[(dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl] ester
• Butanedioic acid, mono[2-[(dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl] ester, [R-(R*,R*)]-
• Chloramphenicol 3-monosuccinate
• Chloramphenicol acid succinate
• Chloramphenicol hemisuccinate
• Chloramphenicol hydrogen succinate
• Chloramphenicol monosuccinate
• Chloromycetin succinate
• Chronicin foam
• Cpsa
• Kemicetine succinate
• Levomycetin hemisuccinate
• Levomycetin succinate
• Paraxin succinate
• Sodium 4-{2-[(Dichloroacetyl)Amino]-3-Hydroxy-3-(4-Nitrophenyl)Propoxy}-4-Oxobutanoate
• Succinato de cloranfenicol
• Succinato de cloranfenicol [Spanish]
• Succinic acid, alpha-monoester with D-threo-(-)-2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl)acetamide
• Succinic acid, ester with chloramphenicol
• Succinic acid, α-monoester with <span class="text-smallcaps">D</span>-threo-(-)-2,2-dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-nitrophenethyl]acetamide
• Chloramphenicol succinate
• 4-13-00-02756 (Beilstein Handbook Reference)
• Acetamide, 2,2-dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-nitrophenethyl]-, α-(hydrogen succinate), D-(-)-threo-

Chloramphenicol Succinate

CAS: 3544-94-3

Formula: C₁₅H₁₆Cl₂N₂O₈

Molecular weight: 423.20 g/mol

Ref: 3W-CS-T-71001

Chloramphenicol succinate

CAS: 3544-94-3

Chloramphenicol succinate

Purity: ≥95%

Molecular weight: 423.2g/mol

Ref: 54-BUP20970

Chloramphenicol Succinate

CAS: 3544-94-3

Formula: C₁₅H₁₆Cl₂N₂O₈

Molecular weight: 423.20

Ref: 4Z-C-10110

Chloramphenicol Succinate

CAS: 3544-94-3

Formula: C₁₅H₁₆Cl₂N₂O₈

Molecular weight: 423.2

Ref: ST-EA-CP-C161008

Chloramphenicol succinate

CAS: 3544-94-3

Chloramphenicol succinate is a bacteriostatic antibiotic. CPSA is a competitive substrate and inhibitor of succinate dehydrogenase (SDH),can be oxidized by.

Formula: C₁₅H₁₆Cl₂N₂O₈

Purity: 95.32%

Color and Shape: Physical Description White Powder (Ntp 1992)

Molecular weight: 423.2

Ref: TM-T25240