CymitQuimica logo

CAS 3545-67-3

:

Chloroquine hydrochloride

Description:
Chloroquine hydrochloride is a synthetic compound primarily known for its use as an antimalarial medication. It is a member of the 4-aminoquinoline class and is characterized by its ability to interfere with the growth of parasites in the red blood cells. The substance appears as a white to off-white crystalline powder and is soluble in water, which facilitates its administration in aqueous solutions. Chloroquine hydrochloride exhibits a basic pH and has a relatively low molecular weight. Its mechanism of action involves the inhibition of heme polymerization within the malaria parasite, leading to toxic accumulation of heme. In addition to its antimalarial properties, chloroquine has also been investigated for its potential use in treating autoimmune diseases such as rheumatoid arthritis and lupus erythematosus. However, its use has been associated with various side effects, including gastrointestinal disturbances and potential retinal toxicity with long-term use. As with any medication, it is essential to use chloroquine hydrochloride under medical supervision to mitigate risks and ensure efficacy.
Formula:C18H26ClN3·2ClH
InChI:InChI=1S/C18H26ClN3.2ClH/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18;;/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21);2*1H
InChI key:InChIKey=PCFGECQRSMVKCC-UHFFFAOYSA-N
SMILES:N(C(CCCN(CC)CC)C)C=1C2=C(N=CC1)C=C(Cl)C=C2.Cl
Synonyms:
  • 1,4-Pentanediamine, N<sup>4</sup>-(7-chloro-4-quinolinyl)-N<sup>1</sup>,N<sup>1</sup>-diethyl-, dihydrochloride
  • 1,4-Pentanediamine, N<sup>4</sup>-(7-chloro-4-quinolinyl)-N<sup>1</sup>,N<sup>1</sup>-diethyl-, hydrochloride (1:2)
  • 7-Chloro-4-(4-diethylamino-1-methylbutylamino)quinoline dihydrochloride
  • Aralen hydrochloride
  • Chloroquine Hydrochloride
  • Chloroquine dihydrochloride
  • N~4~-(7-chloroquinolin-4-yl)-N~1~,N~1~-diethylpentane-1,4-diamine dihydrochloride
  • Quinoline, 7-chloro-4-[[4-(diethylamino)-1-methylbutyl]amino]-, dihydrochloride
  • 1,4-Pentanediamine, N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-, dihydrochloride
  • 1,4-Pentanediamine, N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-, hydrochloride (1:2)
Sort by
The purity filter is not visible because current products do not have associated purity data for filtering.
Found 1 products.