CAS 35455-79-9

2(1H)-Pyrimidinone,3,4-dihydro-5-methyl-4-thioxo-

Description:

2(1H)-Pyrimidinone, 3,4-dihydro-5-methyl-4-thioxo- is a heterocyclic organic compound characterized by a pyrimidine ring structure that incorporates a thioxo group and a methyl substituent. This compound features a dihydro form, indicating the presence of two hydrogen atoms that contribute to its saturation. The thioxo group (–C=S) is a key functional feature, influencing the compound's reactivity and potential applications in medicinal chemistry. The presence of the methyl group at the 5-position of the pyrimidine ring can affect the compound's biological activity and solubility. Generally, compounds of this type may exhibit various pharmacological properties, making them of interest in drug development. The molecular structure allows for potential interactions with biological targets, which can be explored in further research. As with many heterocycles, the stability and reactivity of this compound can be influenced by the electronic effects of the substituents on the ring. Overall, 2(1H)-Pyrimidinone, 3,4-dihydro-5-methyl-4-thioxo- represents a class of compounds with diverse applications in chemistry and pharmacology.

Formula: C₅H₆N₂OS

Synonyms:

• Thymine,4-thio- (7CI,8CI)
• 2-Oxo-4-mercapto-5-methylpyrimidine
• 4-Thio-5-methylpyrimidin-2-one
• 4-Thiothymine
• 5-Methyl-4-thiouracil

2(1H)-Pyrimidinone, 3,4-dihydro-5-methyl-4-thioxo- (9CI)

CAS: 35455-79-9

Formula: C₅H₆N₂OS

Purity: 97%

Color and Shape: Solid

Molecular weight: 142.1789

Ref: IN-DA00CKAN

5-Methyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one

CAS: 35455-79-9

5-Methyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one

Purity: 98%

Molecular weight: 142.18g/mol

Ref: 54-OR82636

5-Methyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one

CAS: 35455-79-9

Formula: C₅H₆N₂OS

Purity: 97%

Molecular weight: 142.18

Ref: 10-F454678

5-Methyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one

CAS: 35455-79-9

5-Methyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one is a compound that interacts with DNA duplexes. It binds to the sugar residues of the DNA duplex in a manner that alters its photophysical and biological properties. 5-Methyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one has been shown to bind to dna binding proteins such as p53 and p300. This compound can also interact with oligodeoxynucleotides and is able to inhibit the synthesis of RNA by interacting with ribonucleotide reductase. The interaction of 5-methyl 4 thioxo 3,4 dihydropyrimidin 2(1H) one with ribonucleotide reductase leads to the formation of silver ions, which are toxic to cells and lead to cell death.

Formula: C₅H₆N₂OS

Purity: Min. 95%

Molecular weight: 142.18 g/mol

Ref: 3D-KBA45579