CAS 3546-21-2
:Ethidium
Description:
Ethidium, with the CAS number 3546-21-2, is a fluorescent intercalating agent commonly used in molecular biology and biochemistry. It is characterized by its ability to intercalate between the base pairs of nucleic acids, which makes it particularly useful for visualizing DNA in gel electrophoresis. Ethidium bromide, the most well-known form of ethidium, emits a bright orange fluorescence when bound to DNA under ultraviolet light, allowing for the detection of nucleic acids. The compound is a cationic dye, which means it carries a positive charge, facilitating its interaction with the negatively charged phosphate backbone of DNA. Ethidium is also known for its potential mutagenic properties, as it can cause DNA damage if not handled properly. Therefore, while it is a valuable tool in laboratory settings, safety precautions are essential due to its toxic and potentially carcinogenic nature. Overall, ethidium serves as an important reagent in various applications, including DNA quantification and analysis.
Formula:C21H20N3
InChI:InChI=1S/C21H19N3/c1-2-24-20-13-16(23)9-11-18(20)17-10-8-15(22)12-19(17)21(24)14-6-4-3-5-7-14/h3-13,23H,2,22H2,1H3/p+1
InChI key:InChIKey=QTANTQQOYSUMLC-UHFFFAOYSA-O
SMILES:C(C)[N+]=1C(=C2C(=C3C1C=C(N)C=C3)C=CC(N)=C2)C4=CC=CC=C4
Synonyms:- Ethidium
- 3,8-Diamino-5-ethyl-6-phenylphenanthridinium
- Phenanthridinium compound, 3,8-diamino-5-ethyl-6-phenyl-
- Homidium
- Phenanthridinium, 3,8-diamino-5-ethyl-6-phenyl-
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Homidium Free Base
CAS:<p>Homidium Free Base is a trypanocidal and potential antiviral agent, binding to DNA, inhibiting receptors, and fluorescing; often used as bromide.</p>Formula:C21H20N3Color and Shape:SolidMolecular weight:314.4
