CAS 354759-10-7

PBOX-15

CAS: 354759-10-7

PBOX-15 is a novel, small molecule that causes mitochondrial membrane depolarization. This leads to the release of cytochrome c and other pro-apoptotic proteins into the cytosol. It also inhibits the BCR-ABL kinase, which is associated with cancer cell proliferation. PBOX-15 has minimal toxicity in animal studies and has been shown to have little effect on drug metabolism. It has been shown to have a potent antiproliferative effect on squamous carcinoma cells and other solid tumours such as breast, prostate, lung, colon, and pancreatic cancers.

Formula: C₂₈H₁₉NO₃

Purity: Min. 95%

Molecular weight: 417.5 g/mol

Ref: 3D-EPA75910

PBOX-15

CAS: 354759-10-7

PBOX-15 induces apoptosis, regulates death receptors, enhances TRAIL effects, and inhibits T cell migration in myeloma cells.

Formula: C₂₈H₁₉NO₃

Color and Shape: Solid

Molecular weight: 417.46

Ref: TM-T33892