CAS 35511-14-9

2H-1,2-Benzothiazine-3-carboxylic acid, 4-hydroxy-, methyl ester, 1,1-dioxide

Description:

2H-1,2-Benzothiazine-3-carboxylic acid, 4-hydroxy-, methyl ester, 1,1-dioxide, commonly referred to as a benzothiazine derivative, exhibits several notable characteristics. This compound features a benzothiazine core, which is a bicyclic structure containing both a benzene ring and a thiazine ring, contributing to its unique chemical properties. The presence of a carboxylic acid group and a methoxy group enhances its solubility in polar solvents and may influence its reactivity and biological activity. The 1,1-dioxide designation indicates the presence of a sulfone functional group, which can enhance the compound's stability and reactivity. This compound may exhibit various biological activities, potentially including anti-inflammatory or antimicrobial properties, making it of interest in pharmaceutical research. Its molecular structure allows for potential interactions with biological targets, and its derivatives may be explored for therapeutic applications. Overall, the characteristics of this compound make it a subject of interest in both synthetic chemistry and medicinal chemistry.

Formula: C₁₀H₉NO₅S

InChI: InChI=1S/C10H9NO5S/c1-16-10(13)8-9(12)6-4-2-3-5-7(6)17(14,15)11-8/h2-5,11-12H,1H3

InChI key: InChIKey=GEUURTZIEGFZAG-UHFFFAOYSA-N

SMILES: O=S1(=O)C=2C(C(O)=C(C(OC)=O)N1)=CC=CC2

Synonyms:

• 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylic acid methyl ester 1,1-dioxide
• 2H-1,2-Benzothiazine-3-carboxylic acid, 4-hydroxy-, methyl ester, 1,1-dioxide
• Methyl 4-hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide

Methyl 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide

CAS: 35511-14-9

Formula: C₁₀H₉NO₅S

Purity: 97%

Color and Shape: Solid

Molecular weight: 255.2472

Ref: IN-DA00BXOQ

Piroxicam EP Impurity G

CAS: 35511-14-9

Formula: C₁₀H₉NO₅S

Color and Shape: Pale Yellow Solid

Molecular weight: 255.24

Ref: 4Z-P-2512

Methyl 4-hydroxy-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide

CAS: 35511-14-9

Methyl 4-hydroxy-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide

Purity: 97%

Molecular weight: 255.25g/mol

Ref: 54-OR1054994

Methyl 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide

Controlled Product

CAS: 35511-14-9

Formula: C₁₀H₉NO₅S

Color and Shape: Neat

Molecular weight: 255.25

Ref: 86-MM0084.04

Piroxicam EP Impurity G

CAS: 35511-14-9

Formula: C₁₀H₉NO₅S

Molecular weight: 255.24

Ref: ST-EA-CP-P22007

Methyl 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide

Controlled Product

CAS: 35511-14-9

Impurity Piroxicam EP Impurity G
Applications Piroxicam impurity G.
References Lombardino, J., et al.: J. Med. Chem., 14, 1171 (1971), Turck, D., et al.: Clin. Pharmacol., 36, 79 (1996), Bihovsky, R., et al.: Bioorg. Med. Chem. Lett., 14, 1035 (2004),

Formula: C₁₀H₉NO₅S

Color and Shape: Neat

Molecular weight: 255.25

Ref: TR-M312590

Methyl 4-hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide

CAS: 35511-14-9

Methyl 4-hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide (MTBC) is a drug target that is a carboxylate. MTBC has been shown to have potent inhibition activity against benzothiazine oxidases. MTBC can be used as an inhibitor of enzymes involved in the biosynthesis of benzothiazines and may be useful for the treatment of diseases such as Parkinson's disease and schizophrenia. The inhibition potential of MTBC has been unraveled through its interaction with peroxidases and other oxidases. In vitro studies have shown that MTBC can inhibit the oxidation of low molecular weight compounds by acting as a scavenger for hydrogen peroxide. This drug also exhibits unsymmetrical dehydration to produce methyl 4-(hydroxyamino)-2H-1,2-benzothiazine 1,1-dioxoate (MTBA), which is an

Formula: C₁₀H₉NO₅S

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 255.25 g/mol

Ref: 3D-IM25440