CAS 355129-15-6

Eprotirome

Description:

Eprotirome, also known by its chemical name, is a synthetic thyroid hormone analog primarily designed for the treatment of dyslipidemia and related cardiovascular conditions. It functions as a selective thyroid hormone receptor beta agonist, which means it selectively activates the beta subtype of thyroid hormone receptors, leading to increased metabolism and improved lipid profiles without the full spectrum of thyroid hormone effects. Eprotirome has been shown to lower levels of low-density lipoprotein (LDL) cholesterol and triglycerides while potentially minimizing the side effects associated with traditional thyroid hormone therapies. Its pharmacokinetics indicate a favorable absorption profile, and it is typically administered orally. The compound has undergone various clinical trials to assess its efficacy and safety, particularly in patients with elevated cholesterol levels. However, as with any medication, potential side effects and contraindications should be considered, and its use should be guided by a healthcare professional. Overall, eprotirome represents a targeted approach to managing lipid disorders through modulation of thyroid hormone activity.

Formula: C₁₈H₁₇Br₂NO₅

InChI: InChI=1S/C18H17Br2NO5/c1-9(2)12-7-11(3-4-15(12)22)26-18-13(19)5-10(6-14(18)20)21-16(23)8-17(24)25/h3-7,9,22H,8H2,1-2H3,(H,21,23)(H,24,25)

InChI key: InChIKey=VPCSYAVXDAUHLT-UHFFFAOYSA-N

SMILES: O(C1=C(Br)C=C(NC(CC(O)=O)=O)C=C1Br)C2=CC(C(C)C)=C(O)C=C2

Synonyms:

• 3-((3,5-Dibromo-4-(4-hydroxy-3-isopropylphenoxy)phenyl)amino)-3-oxopropanoic acid
• 3-[3,5-Dibromo-4-(4-hydroxy-3-isopropylphenoxy)anilino]-3-oxo-propanoic acid
• 3-[[3,5-Dibromo-4-[4-hydroxy-3-(1-methylethyl)phenoxy]phenyl]amino]-3-oxopropanoic acid
• Kb 2115
• N-[3,5-Dibromo-4-(4-hydroxy-3-isopropylphenoxy)phenyl]malonamic acid
• Propanoic acid, 3-[[3,5-dibromo-4-[4-hydroxy-3-(1-methylethyl)phenoxy]phenyl]amino]-3-oxo-
• Eprotirome

Eprotirome

CAS: 355129-15-6

Formula: C₁₈H₁₇Br₂NO₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 487.1393

Ref: IN-DA00C0VS

3-((3,5-Dibromo-4-(4-Hydroxy-3-Isopropylphenoxy)Phenyl)Amino)-3-Oxopropanoic Acid

CAS: 355129-15-6

3-((3,5-Dibromo-4-(4-Hydroxy-3-Isopropylphenoxy)Phenyl)Amino)-3-Oxopropanoic Acid

Purity: 98%

Molecular weight: 487.14g/mol

Ref: 54-OR1024047

Eprotirome

CAS: 355129-15-6

Eprotirome

Purity: ≥98%

Molecular weight: 487.14g/mol

Ref: 54-BUP09052

Eprotirome

CAS: 355129-15-6

Eprotirome (KB2115), a synthetic thyroid hormone mimetic, is a thyroid hormone receptor agonist.

Formula: C₁₈H₁₇Br₂NO₅

Purity: 98.42% - 98.56%

Color and Shape: Solid

Molecular weight: 487.14

Ref: TM-T5360

EPROTIROME

CAS: 355129-15-6

Purity: 98%

Molecular weight: 487.1440125

Ref: 10-F811870