CAS 355140-49-7

Ac-Nle-Pro-Nle-Asp-AMC

CAS: 355140-49-7

Ac-nLPnLD-AMC, substrate for proteasome.

Formula: C₃₃H₄₅N₅O₉

Purity: 97.34%

Color and Shape: White Powder

Molecular weight: 655.75

Ref: 01-4030084

(S)-3-((S)-2-((S)-1-((S)-2-Acetamidohexanoyl)pyrrolidine-2-carboxamido)hexanamido)-4-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-4-oxobutanoic acid

CAS: 355140-49-7

(S)-3-((S)-2-((S)-1-((S)-2-Acetamidohexanoyl)pyrrolidine-2-carboxamido)hexanamido)-4-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-4-oxobutanoic acid

Purity: 98%

Molecular weight: 655.75g/mol

Ref: 54-OR1062989

Ac-Nle-Pro-Nle-Asp-AMC

CAS: 355140-49-7

Ac-Nle-Pro-Nle-Asp-AMC is a reactive molecule that has been shown to be neuroprotective and to inhibit insulin resistance in mammalian cells. Ac-Nle-Pro-Nle-Asp-AMC is able to stop neuronal death by binding to the proteolytic enzymes, such as ubiquitin ligases, and inhibiting their activity. This drug also inhibits the activity of c2c12 myotubes, which are muscle cells that have been used in research studies. Ac-Nle-Pro-Nle-Asp AMC binds to ubiquitin and prevents it from being degraded by the proteasome system, which is a cellular protein degradation pathway. Ac-Nle-Pro-Nle -Asp AMC also inhibits the release of inflammatory factors from c2c12 myotubes, which may be due to its ability to block ubiquitin ligases.

Formula: C₃₃H₄₅N₅O₉

Purity: Min. 97 Area-%

Color and Shape: Powder

Molecular weight: 655.74 g/mol

Ref: 3D-FA110588